Enhancement of material attributes of poorly compressible metformin hydrochloride through coprocessing with hydroxypropyl cellulose (HPC-L) using coprecipitation (CPT)

Enhancement of material attributes of poorly compressible metformin hydrochloride through coprocessing with hydroxypropyl cellulose (HPC-L) using coprecipitation (CPT)

Abstract Coprocessing involves integration of multiple substances to improve the physical, chemical, mechanical, and biopharmaceutical properties of a material. Coprocessing is a promising technique in the pharmaceutical industry which support both drug substance and drug product processes. When act...

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Bibliographic Details
Main Authors: Kaushalendra Chaturvedi, Pasaorn Pongkulapa, Xiaoyi Ding, Harsh S. Shah, San Kiang, Veeran Kadajji
Format: Article
Language:English
Published: SpringerOpen 2023-11-01
Series:AAPS Open
Subjects:
Metformin hydrochloride
Coprocessing
Coprecipitation
Direct compression
HPC-L
Online Access:https://doi.org/10.1186/s41120-023-00088-3

Internet

https://doi.org/10.1186/s41120-023-00088-3

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