Assessment of the mutagenic potential of Skadar Lake sediments using the salmonella microsomal assay

Organic extracts of sediments from Skadar Lake (National park and protected RAMSAR site) were investigated for their mutagenic potential using Salmonella typhimurium TA98 and TA100 strains in the presence and absence of metabolic activation. Five different concentrations of sediment extracts from...

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Main Authors: Perović Svetlana, Perović A., Erdinger L., Hollert H.
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2013-01-01
Series:Archives of Biological Sciences
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2013/0354-46641303189P.pdf
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author Perović Svetlana
Perović A.
Erdinger L.
Hollert H.
author_facet Perović Svetlana
Perović A.
Erdinger L.
Hollert H.
author_sort Perović Svetlana
collection DOAJ
description Organic extracts of sediments from Skadar Lake (National park and protected RAMSAR site) were investigated for their mutagenic potential using Salmonella typhimurium TA98 and TA100 strains in the presence and absence of metabolic activation. Five different concentrations of sediment extracts from five different sampling sites were assayed, and mutagenic results were obtained for both strains. These studies present a part of the EULIMNOS project and included a battery of bioassay testing and in situ investigations of microbial community structures of Skadar Lake sediments. The obtained results show mutagenic risk potential in five collected samples in the absence and presence of metabolic activation. Additional studies are required in order to identify and quantify the chemical compounds responsible for the mutagenic activity present in Skadar Lake sediments.
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spelling doaj.art-818c4af2e1f441db8d120fd855fb70702022-12-22T03:49:17ZengUniversity of Belgrade, University of Novi SadArchives of Biological Sciences0354-46641821-43392013-01-016531189119410.2298/ABS1303189PAssessment of the mutagenic potential of Skadar Lake sediments using the salmonella microsomal assayPerović SvetlanaPerović A.Erdinger L.Hollert H.Organic extracts of sediments from Skadar Lake (National park and protected RAMSAR site) were investigated for their mutagenic potential using Salmonella typhimurium TA98 and TA100 strains in the presence and absence of metabolic activation. Five different concentrations of sediment extracts from five different sampling sites were assayed, and mutagenic results were obtained for both strains. These studies present a part of the EULIMNOS project and included a battery of bioassay testing and in situ investigations of microbial community structures of Skadar Lake sediments. The obtained results show mutagenic risk potential in five collected samples in the absence and presence of metabolic activation. Additional studies are required in order to identify and quantify the chemical compounds responsible for the mutagenic activity present in Skadar Lake sediments.http://www.doiserbia.nb.rs/img/doi/0354-4664/2013/0354-46641303189P.pdfSkadar Lakesediment extractsmutagenic activitySalmonella typhimurium TA98 and TA100
spellingShingle Perović Svetlana
Perović A.
Erdinger L.
Hollert H.
Assessment of the mutagenic potential of Skadar Lake sediments using the salmonella microsomal assay
Archives of Biological Sciences
Skadar Lake
sediment extracts
mutagenic activity
Salmonella typhimurium TA98 and TA100
title Assessment of the mutagenic potential of Skadar Lake sediments using the salmonella microsomal assay
title_full Assessment of the mutagenic potential of Skadar Lake sediments using the salmonella microsomal assay
title_fullStr Assessment of the mutagenic potential of Skadar Lake sediments using the salmonella microsomal assay
title_full_unstemmed Assessment of the mutagenic potential of Skadar Lake sediments using the salmonella microsomal assay
title_short Assessment of the mutagenic potential of Skadar Lake sediments using the salmonella microsomal assay
title_sort assessment of the mutagenic potential of skadar lake sediments using the salmonella microsomal assay
topic Skadar Lake
sediment extracts
mutagenic activity
Salmonella typhimurium TA98 and TA100
url http://www.doiserbia.nb.rs/img/doi/0354-4664/2013/0354-46641303189P.pdf
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AT perovica assessmentofthemutagenicpotentialofskadarlakesedimentsusingthesalmonellamicrosomalassay
AT erdingerl assessmentofthemutagenicpotentialofskadarlakesedimentsusingthesalmonellamicrosomalassay
AT hollerth assessmentofthemutagenicpotentialofskadarlakesedimentsusingthesalmonellamicrosomalassay