A Normalization Protocol Reduces Edge Effect in High-Throughput Analyses of Hydroxyurea Hypersensitivity in Fission Yeast

A Normalization Protocol Reduces Edge Effect in High-Throughput Analyses of Hydroxyurea Hypersensitivity in Fission Yeast

Edge effect denotes better growth of microbial organisms situated at the edge of the solid agar media. Although the precise reason underlying edge effect is unresolved, it is generally attributed to greater nutrient availability with less competing neighbors at the edge. Nonetheless, edge effect con...

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Bibliographic Details
Main Authors: Ulysses Tsz-Fung Lam, Thi Thuy Trang Nguyen, Raechell Raechell, Jay Yang, Harry Singer, Ee Sin Chen
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biomedicines
Subjects:
drug screening
yeast
edge effect
high-throughput screening
<i>Schizosaccharomyces pombe</i>
fission yeast
Online Access:https://www.mdpi.com/2227-9059/11/10/2829

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