Interferon-Gamma Primed Human Clonal Mesenchymal Stromal Cell Sheets Exhibit Enhanced Immunosuppressive Function

Interferon-Gamma Primed Human Clonal Mesenchymal Stromal Cell Sheets Exhibit Enhanced Immunosuppressive Function

Mesenchymal stromal cells (MSCs) represent a promising treatment for immune-related diseases due to their diverse immunomodulatory paracrine functions. However, progress of culture-expanded MSCs is hindered by inconsistent cell function, poor localization, and insufficient retention when administere...

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Bibliographic Details
Main Authors: Celia M. Dunn, Sumako Kameishi, Yun-Kyoung Cho, Sun U. Song, David W. Grainger, Teruo Okano
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
mesenchymal stem cells
immunomodulation
pre-conditioning
licensing
tissue engineering
cellular therapy
Online Access:https://www.mdpi.com/2073-4409/11/23/3738

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