Posttransplantation tuberculosis management in terms of immunosuppressant cost: a case report in Myanmar
Drug interactions between anti-tuberculosis and immunosuppressive medications after renal transplantation are a common problem in Myanmar. The efficacy of both types of drugs can be reduced during the treatment period, which can lead to graft failure and flare-ups of infection. Drug adjustments, wit...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Korean Society for Transplantation
2021-03-01
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| Series: | Korean Journal of Transplantation |
| Subjects: | |
| Online Access: | http://journaleditor.inforang.com/journal/view.html?doi=10.4285/kjt.20.0041 |
| _version_ | 1797334869579137024 |
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| author | Phyo Wai Lwin Yi Yi Htun Aung Kyaw Myint Htar Kyi Swe |
| author_facet | Phyo Wai Lwin Yi Yi Htun Aung Kyaw Myint Htar Kyi Swe |
| author_sort | Phyo Wai Lwin |
| collection | DOAJ |
| description | Drug interactions between anti-tuberculosis and immunosuppressive medications after renal transplantation are a common problem in Myanmar. The efficacy of both types of drugs can be reduced during the treatment period, which can lead to graft failure and flare-ups of infection. Drug adjustments, with frequent monitoring and close follow-up, are crucial in this period. Ketoconazole decreases tacrolimus metabolism by inhibiting cytochrome P450-3A5 enzymes and P-glycoprotein. It is cost effective and has been frequently used to reduce the dose and cost of tacrolimus. Here, we report the case of a 56-year-old male renal transplant recipient with anti-tuberculosis medications. |
| first_indexed | 2024-03-08T08:27:30Z |
| format | Article |
| id | doaj.art-818f9737db0f4acfb1f8033df9d4725f |
| institution | Directory Open Access Journal |
| issn | 2671-8790 |
| language | English |
| last_indexed | 2024-03-08T08:27:30Z |
| publishDate | 2021-03-01 |
| publisher | Korean Society for Transplantation |
| record_format | Article |
| series | Korean Journal of Transplantation |
| spelling | doaj.art-818f9737db0f4acfb1f8033df9d4725f2024-02-02T04:20:12ZengKorean Society for TransplantationKorean Journal of Transplantation2671-87902021-03-01351485210.4285/kjt.20.0041kjt.20.0041Posttransplantation tuberculosis management in terms of immunosuppressant cost: a case report in MyanmarPhyo Wai Lwin0Yi Yi Htun1Aung Kyaw Myint2Htar Kyi Swe3Department of Nephrology, University of Medicine, Mandalay, Mandalay, MyanmarDepartment of Pharmacology, University of Medicine, Mandalay, Mandalay, MyanmarDepartment of Nephrology, Mandalay General Hospital, Mandalay, MyanmarDepartment of Nephrology, University of Medicine, Mandalay, Mandalay, MyanmarDrug interactions between anti-tuberculosis and immunosuppressive medications after renal transplantation are a common problem in Myanmar. The efficacy of both types of drugs can be reduced during the treatment period, which can lead to graft failure and flare-ups of infection. Drug adjustments, with frequent monitoring and close follow-up, are crucial in this period. Ketoconazole decreases tacrolimus metabolism by inhibiting cytochrome P450-3A5 enzymes and P-glycoprotein. It is cost effective and has been frequently used to reduce the dose and cost of tacrolimus. Here, we report the case of a 56-year-old male renal transplant recipient with anti-tuberculosis medications.http://journaleditor.inforang.com/journal/view.html?doi=10.4285/kjt.20.0041post renal transplant tuberculosis; immunosuppressant cost; drug interaction |
| spellingShingle | Phyo Wai Lwin Yi Yi Htun Aung Kyaw Myint Htar Kyi Swe Posttransplantation tuberculosis management in terms of immunosuppressant cost: a case report in Myanmar Korean Journal of Transplantation post renal transplant tuberculosis; immunosuppressant cost; drug interaction |
| title | Posttransplantation tuberculosis management in terms of immunosuppressant cost: a case report in Myanmar |
| title_full | Posttransplantation tuberculosis management in terms of immunosuppressant cost: a case report in Myanmar |
| title_fullStr | Posttransplantation tuberculosis management in terms of immunosuppressant cost: a case report in Myanmar |
| title_full_unstemmed | Posttransplantation tuberculosis management in terms of immunosuppressant cost: a case report in Myanmar |
| title_short | Posttransplantation tuberculosis management in terms of immunosuppressant cost: a case report in Myanmar |
| title_sort | posttransplantation tuberculosis management in terms of immunosuppressant cost a case report in myanmar |
| topic | post renal transplant tuberculosis; immunosuppressant cost; drug interaction |
| url | http://journaleditor.inforang.com/journal/view.html?doi=10.4285/kjt.20.0041 |
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