Microwave-Assisted Synthesis of Bioactive Six-Membered Heterocycles and Their Fused Analogues
This review describes the formation of six-membered heterocyclic compounds and their fused analogues under microwave activation using modern organic transformations including cyclocondensation, cycloaddition, multicomponents and other modular reactions. The review is divided according to the main he...
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Format: | Article |
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MDPI AG
2016-04-01
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Series: | Molecules |
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Online Access: | http://www.mdpi.com/1420-3049/21/4/492 |
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author | Mohsine Driowya Aziza Saber Hamid Marzag Luc Demange Rachid Benhida Khalid Bougrin |
author_facet | Mohsine Driowya Aziza Saber Hamid Marzag Luc Demange Rachid Benhida Khalid Bougrin |
author_sort | Mohsine Driowya |
collection | DOAJ |
description | This review describes the formation of six-membered heterocyclic compounds and their fused analogues under microwave activation using modern organic transformations including cyclocondensation, cycloaddition, multicomponents and other modular reactions. The review is divided according to the main heterocycle types in order of increasing complexity, starting with heterocyclic systems containing one, two and three heteroatoms and their fused analogues. Recent microwave applications are reviewed, with special focus on the chemistry of bioactive compounds. Selected examples from the 2006 to 2015 literature are discussed. |
first_indexed | 2024-12-21T01:14:30Z |
format | Article |
id | doaj.art-8190761d52194709941a69195ddc93a4 |
institution | Directory Open Access Journal |
issn | 1420-3049 |
language | English |
last_indexed | 2024-12-21T01:14:30Z |
publishDate | 2016-04-01 |
publisher | MDPI AG |
record_format | Article |
series | Molecules |
spelling | doaj.art-8190761d52194709941a69195ddc93a42022-12-21T19:20:49ZengMDPI AGMolecules1420-30492016-04-0121449210.3390/molecules21040492molecules21040492Microwave-Assisted Synthesis of Bioactive Six-Membered Heterocycles and Their Fused AnaloguesMohsine Driowya0Aziza Saber1Hamid Marzag2Luc Demange3Rachid Benhida4Khalid Bougrin5Laboratoire de Chimie des Plantes et de Synthèse Organique et Bioorganique, URAC23, Faculté des Sciences, Université Mohammed V, B.P. 1014 Rabat, MarocLaboratoire de Chimie des Plantes et de Synthèse Organique et Bioorganique, URAC23, Faculté des Sciences, Université Mohammed V, B.P. 1014 Rabat, MarocLaboratoire de Chimie des Plantes et de Synthèse Organique et Bioorganique, URAC23, Faculté des Sciences, Université Mohammed V, B.P. 1014 Rabat, MarocInstitut de Chimie de Nice, ICN UMR UNS CNRS 7272, Université Nice-Sophia Antipolis-Université Côte d’Azur, Parc Valrose, 06108 Nice Cedex 2, FranceInstitut de Chimie de Nice, ICN UMR UNS CNRS 7272, Université Nice-Sophia Antipolis-Université Côte d’Azur, Parc Valrose, 06108 Nice Cedex 2, FranceLaboratoire de Chimie des Plantes et de Synthèse Organique et Bioorganique, URAC23, Faculté des Sciences, Université Mohammed V, B.P. 1014 Rabat, MarocThis review describes the formation of six-membered heterocyclic compounds and their fused analogues under microwave activation using modern organic transformations including cyclocondensation, cycloaddition, multicomponents and other modular reactions. The review is divided according to the main heterocycle types in order of increasing complexity, starting with heterocyclic systems containing one, two and three heteroatoms and their fused analogues. Recent microwave applications are reviewed, with special focus on the chemistry of bioactive compounds. Selected examples from the 2006 to 2015 literature are discussed.http://www.mdpi.com/1420-3049/21/4/492microwave irradiationbioactive moleculescycloadditioncyclocondensationmulticomponent reactions |
spellingShingle | Mohsine Driowya Aziza Saber Hamid Marzag Luc Demange Rachid Benhida Khalid Bougrin Microwave-Assisted Synthesis of Bioactive Six-Membered Heterocycles and Their Fused Analogues Molecules microwave irradiation bioactive molecules cycloaddition cyclocondensation multicomponent reactions |
title | Microwave-Assisted Synthesis of Bioactive Six-Membered Heterocycles and Their Fused Analogues |
title_full | Microwave-Assisted Synthesis of Bioactive Six-Membered Heterocycles and Their Fused Analogues |
title_fullStr | Microwave-Assisted Synthesis of Bioactive Six-Membered Heterocycles and Their Fused Analogues |
title_full_unstemmed | Microwave-Assisted Synthesis of Bioactive Six-Membered Heterocycles and Their Fused Analogues |
title_short | Microwave-Assisted Synthesis of Bioactive Six-Membered Heterocycles and Their Fused Analogues |
title_sort | microwave assisted synthesis of bioactive six membered heterocycles and their fused analogues |
topic | microwave irradiation bioactive molecules cycloaddition cyclocondensation multicomponent reactions |
url | http://www.mdpi.com/1420-3049/21/4/492 |
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