Carotid Artery Stenting, Endarterectomy, or Medical Treatment Alone: The Debate Is Not Over

The management of carotid artery stenosis reduces the risk of stroke and its related deaths. Management options include risk factor modification and medical therapy, carotid endarterectomy (CEA), and carotid artery stenting (CAS). Although several randomized controlled trials (RCTs), mostly conducte...

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Main Authors: Hamidreza Goodarzynejad, Seyed Ebrahim Kassaian
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2011-02-01
Series:Journal of Tehran University Heart Center
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/17545.pdf&manuscript_id=17545
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author Hamidreza Goodarzynejad
Seyed Ebrahim Kassaian
author_facet Hamidreza Goodarzynejad
Seyed Ebrahim Kassaian
author_sort Hamidreza Goodarzynejad
collection DOAJ
description The management of carotid artery stenosis reduces the risk of stroke and its related deaths. Management options include risk factor modification and medical therapy, carotid endarterectomy (CEA), and carotid artery stenting (CAS). Although several randomized controlled trials (RCTs), mostly conducted in late-1980s and mid-1990s, have proved CEA to be effective in the prevention of ipsilateral ischemic events in selected patients with carotid artery stenosis, aggressive risk factor modification and medical therapy with recently introduced antiplatelet agents, statins, and more effective antihypertensive medications may have reduced compelling indications for immediate surgery in asymptomatic populations. Also recently, due to improvements in percutaneous techniques and carotid stents, CAS has received wide attention as a potential alternative to CEA. Herein, we review the recent data on the management options of carotid artery stenosis and seek to identify the most appropriate treatment strategy in selected patients with carotid artery stenosis.
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spelling doaj.art-8191d0ed0f3447b59c9dc9493f4baa122022-12-21T18:15:07ZengTehran University of Medical SciencesJournal of Tehran University Heart Center1735-86202011-02-0161113Carotid Artery Stenting, Endarterectomy, or Medical Treatment Alone: The Debate Is Not OverHamidreza GoodarzynejadSeyed Ebrahim KassaianThe management of carotid artery stenosis reduces the risk of stroke and its related deaths. Management options include risk factor modification and medical therapy, carotid endarterectomy (CEA), and carotid artery stenting (CAS). Although several randomized controlled trials (RCTs), mostly conducted in late-1980s and mid-1990s, have proved CEA to be effective in the prevention of ipsilateral ischemic events in selected patients with carotid artery stenosis, aggressive risk factor modification and medical therapy with recently introduced antiplatelet agents, statins, and more effective antihypertensive medications may have reduced compelling indications for immediate surgery in asymptomatic populations. Also recently, due to improvements in percutaneous techniques and carotid stents, CAS has received wide attention as a potential alternative to CEA. Herein, we review the recent data on the management options of carotid artery stenosis and seek to identify the most appropriate treatment strategy in selected patients with carotid artery stenosis.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/17545.pdf&manuscript_id=17545Carotid StenosisEndarterectomy- CarotidStroke
spellingShingle Hamidreza Goodarzynejad
Seyed Ebrahim Kassaian
Carotid Artery Stenting, Endarterectomy, or Medical Treatment Alone: The Debate Is Not Over
Journal of Tehran University Heart Center
Carotid Stenosis
Endarterectomy- Carotid
Stroke
title Carotid Artery Stenting, Endarterectomy, or Medical Treatment Alone: The Debate Is Not Over
title_full Carotid Artery Stenting, Endarterectomy, or Medical Treatment Alone: The Debate Is Not Over
title_fullStr Carotid Artery Stenting, Endarterectomy, or Medical Treatment Alone: The Debate Is Not Over
title_full_unstemmed Carotid Artery Stenting, Endarterectomy, or Medical Treatment Alone: The Debate Is Not Over
title_short Carotid Artery Stenting, Endarterectomy, or Medical Treatment Alone: The Debate Is Not Over
title_sort carotid artery stenting endarterectomy or medical treatment alone the debate is not over
topic Carotid Stenosis
Endarterectomy- Carotid
Stroke
url http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/17545.pdf&manuscript_id=17545
work_keys_str_mv AT hamidrezagoodarzynejad carotidarterystentingendarterectomyormedicaltreatmentalonethedebateisnotover
AT seyedebrahimkassaian carotidarterystentingendarterectomyormedicaltreatmentalonethedebateisnotover