The Promise of Nanotechnology in Personalized Medicine
Both personalized medicine and nanomedicine are new to medical practice. Nanomedicine is an application of the advances of nanotechnology in medicine and is being integrated into diagnostic and therapeutic tools to manage an array of medical conditions. On the other hand, personalized medicine, whic...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-04-01
|
| Series: | Journal of Personalized Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4426/12/5/673 |
| _version_ | 1797498677719203840 |
|---|---|
| author | Maha Ali Alghamdi Antonino N. Fallica Nicola Virzì Prashant Kesharwani Valeria Pittalà Khaled Greish |
| author_facet | Maha Ali Alghamdi Antonino N. Fallica Nicola Virzì Prashant Kesharwani Valeria Pittalà Khaled Greish |
| author_sort | Maha Ali Alghamdi |
| collection | DOAJ |
| description | Both personalized medicine and nanomedicine are new to medical practice. Nanomedicine is an application of the advances of nanotechnology in medicine and is being integrated into diagnostic and therapeutic tools to manage an array of medical conditions. On the other hand, personalized medicine, which is also referred to as precision medicine, is a novel concept that aims to individualize/customize therapeutic management based on the personal attributes of the patient to overcome blanket treatment that is only efficient in a subset of patients, leaving others with either ineffective treatment or treatment that results in significant toxicity. Novel nanomedicines have been employed in the treatment of several diseases, which can be adapted to each patient-specific case according to their genetic profiles. In this review, we discuss both areas and the intersection between the two emerging scientific domains. The review focuses on the current situation in personalized medicine, the advantages that can be offered by nanomedicine to personalized medicine, and the application of nanoconstructs in the diagnosis of genetic variability that can identify the right drug for the right patient. Finally, we touch upon the challenges in both fields towards the translation of nano-personalized medicine. |
| first_indexed | 2024-03-10T03:36:46Z |
| format | Article |
| id | doaj.art-8192ea5376bb4460863dd9b95253ceba |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-10T03:36:46Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-8192ea5376bb4460863dd9b95253ceba2023-11-23T11:42:57ZengMDPI AGJournal of Personalized Medicine2075-44262022-04-0112567310.3390/jpm12050673The Promise of Nanotechnology in Personalized MedicineMaha Ali Alghamdi0Antonino N. Fallica1Nicola Virzì2Prashant Kesharwani3Valeria Pittalà4Khaled Greish5Department of Biotechnology, College of science, Taif University, Taif 21974, Saudi ArabiaDepartment of Drug and Health Sciences, University of Catania, 95125 Catania, ItalyDepartment of Drug and Health Sciences, University of Catania, 95125 Catania, ItalyDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, IndiaDepartment of Drug and Health Sciences, University of Catania, 95125 Catania, ItalyDepartment of Molecular Medicine, Princess Al-Jawhara Centre for Molecular Medicine, College of Medicine and Medical Sciences, Arabian Gulf University, Manama 329, BahrainBoth personalized medicine and nanomedicine are new to medical practice. Nanomedicine is an application of the advances of nanotechnology in medicine and is being integrated into diagnostic and therapeutic tools to manage an array of medical conditions. On the other hand, personalized medicine, which is also referred to as precision medicine, is a novel concept that aims to individualize/customize therapeutic management based on the personal attributes of the patient to overcome blanket treatment that is only efficient in a subset of patients, leaving others with either ineffective treatment or treatment that results in significant toxicity. Novel nanomedicines have been employed in the treatment of several diseases, which can be adapted to each patient-specific case according to their genetic profiles. In this review, we discuss both areas and the intersection between the two emerging scientific domains. The review focuses on the current situation in personalized medicine, the advantages that can be offered by nanomedicine to personalized medicine, and the application of nanoconstructs in the diagnosis of genetic variability that can identify the right drug for the right patient. Finally, we touch upon the challenges in both fields towards the translation of nano-personalized medicine.https://www.mdpi.com/2075-4426/12/5/673nanomedicinepersonalized medicinepharmacogeneticspharmacokinetics |
| spellingShingle | Maha Ali Alghamdi Antonino N. Fallica Nicola Virzì Prashant Kesharwani Valeria Pittalà Khaled Greish The Promise of Nanotechnology in Personalized Medicine Journal of Personalized Medicine nanomedicine personalized medicine pharmacogenetics pharmacokinetics |
| title | The Promise of Nanotechnology in Personalized Medicine |
| title_full | The Promise of Nanotechnology in Personalized Medicine |
| title_fullStr | The Promise of Nanotechnology in Personalized Medicine |
| title_full_unstemmed | The Promise of Nanotechnology in Personalized Medicine |
| title_short | The Promise of Nanotechnology in Personalized Medicine |
| title_sort | promise of nanotechnology in personalized medicine |
| topic | nanomedicine personalized medicine pharmacogenetics pharmacokinetics |
| url | https://www.mdpi.com/2075-4426/12/5/673 |
| work_keys_str_mv | AT mahaalialghamdi thepromiseofnanotechnologyinpersonalizedmedicine AT antoninonfallica thepromiseofnanotechnologyinpersonalizedmedicine AT nicolavirzi thepromiseofnanotechnologyinpersonalizedmedicine AT prashantkesharwani thepromiseofnanotechnologyinpersonalizedmedicine AT valeriapittala thepromiseofnanotechnologyinpersonalizedmedicine AT khaledgreish thepromiseofnanotechnologyinpersonalizedmedicine AT mahaalialghamdi promiseofnanotechnologyinpersonalizedmedicine AT antoninonfallica promiseofnanotechnologyinpersonalizedmedicine AT nicolavirzi promiseofnanotechnologyinpersonalizedmedicine AT prashantkesharwani promiseofnanotechnologyinpersonalizedmedicine AT valeriapittala promiseofnanotechnologyinpersonalizedmedicine AT khaledgreish promiseofnanotechnologyinpersonalizedmedicine |