Acute encephalopathy with biphasic seizures and late reduced diffusion associated with Streptococcus sanguinis sepsis
Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) develops in association with systemic as well as central nervous system (CNS) viral or bacterial infections. AESD is most often noted with influenza or human herpesvirus 6 infection in previously healthy infants. However,...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2018-03-01
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| Series: | Pediatric Reports |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/pr/article/view/7424 |
| _version_ | 1818964379098415104 |
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| author | Hitoshi Awaguni Jun Shinozuka Shin-ichiro Tanaka Sayaka Kadowaki Shigeru Makino Rikken Maruyama Yosuke Shigematsu Kenji Hamaoka Shinsaku Imashuku |
| author_facet | Hitoshi Awaguni Jun Shinozuka Shin-ichiro Tanaka Sayaka Kadowaki Shigeru Makino Rikken Maruyama Yosuke Shigematsu Kenji Hamaoka Shinsaku Imashuku |
| author_sort | Hitoshi Awaguni |
| collection | DOAJ |
| description | Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) develops in association with systemic as well as central nervous system (CNS) viral or bacterial infections. AESD is most often noted with influenza or human herpesvirus 6 infection in previously healthy infants. However, AESD has also been reported in an infant with developmental retardation and in a mentally and motor-disabled adolescent. Here, we report the case of a 4-year-old female with significant development delay due to spinal muscular atrophy, who developed AESD during Streptococcus sanguinis sepsis with no apparent CNS infection. Although the patient had extremely high serum procalcitonin (45.84 ng/mL, reference; <0.4) on admission indicating a poor prognosis, she was successfully managed for sepsis and AESD. |
| first_indexed | 2024-12-20T13:00:10Z |
| format | Article |
| id | doaj.art-81955f8e6e4e4449a4e1262894b4b2d1 |
| institution | Directory Open Access Journal |
| issn | 2036-749X 2036-7503 |
| language | English |
| last_indexed | 2024-12-20T13:00:10Z |
| publishDate | 2018-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pediatric Reports |
| spelling | doaj.art-81955f8e6e4e4449a4e1262894b4b2d12022-12-21T19:39:56ZengMDPI AGPediatric Reports2036-749X2036-75032018-03-0110110.4081/pr.2018.74243899Acute encephalopathy with biphasic seizures and late reduced diffusion associated with Streptococcus sanguinis sepsisHitoshi Awaguni0Jun Shinozuka1Shin-ichiro Tanaka2Sayaka Kadowaki3Shigeru Makino4Rikken Maruyama5Yosuke Shigematsu6Kenji Hamaoka7Shinsaku Imashuku8Division of Pediatrics, Uji-Tokushukai Medical Center, Uji, KyotoDivision of Pediatrics, Uji-Tokushukai Medical Center, Uji, KyotoDivision of Pediatrics, Uji-Tokushukai Medical Center, Uji, KyotoDivision of Pediatrics, Uji-Tokushukai Medical Center, Uji, KyotoDivision of Pediatrics, Uji-Tokushukai Medical Center, Uji, KyotoDivision of Pediatrics, Uji-Tokushukai Medical Center, Uji, KyotoDivision of Pediatrics, Uji-Tokushukai Medical Center, Uji, KyotoDivision of Pediatrics, Uji-Tokushukai Medical Center, Uji, KyotoDivision of Pediatrics, Uji-Tokushukai Medical Center, Uji, KyotoAcute encephalopathy with biphasic seizures and late reduced diffusion (AESD) develops in association with systemic as well as central nervous system (CNS) viral or bacterial infections. AESD is most often noted with influenza or human herpesvirus 6 infection in previously healthy infants. However, AESD has also been reported in an infant with developmental retardation and in a mentally and motor-disabled adolescent. Here, we report the case of a 4-year-old female with significant development delay due to spinal muscular atrophy, who developed AESD during Streptococcus sanguinis sepsis with no apparent CNS infection. Although the patient had extremely high serum procalcitonin (45.84 ng/mL, reference; <0.4) on admission indicating a poor prognosis, she was successfully managed for sepsis and AESD.http://www.pagepress.org/journals/index.php/pr/article/view/7424Acute encephalopathy with biphasic seizures and reduced diffusion, AESD, spinal muscular atrophy, Streptococcus sanguinis, sepsis |
| spellingShingle | Hitoshi Awaguni Jun Shinozuka Shin-ichiro Tanaka Sayaka Kadowaki Shigeru Makino Rikken Maruyama Yosuke Shigematsu Kenji Hamaoka Shinsaku Imashuku Acute encephalopathy with biphasic seizures and late reduced diffusion associated with Streptococcus sanguinis sepsis Pediatric Reports Acute encephalopathy with biphasic seizures and reduced diffusion, AESD, spinal muscular atrophy, Streptococcus sanguinis, sepsis |
| title | Acute encephalopathy with biphasic seizures and late reduced diffusion associated with Streptococcus sanguinis sepsis |
| title_full | Acute encephalopathy with biphasic seizures and late reduced diffusion associated with Streptococcus sanguinis sepsis |
| title_fullStr | Acute encephalopathy with biphasic seizures and late reduced diffusion associated with Streptococcus sanguinis sepsis |
| title_full_unstemmed | Acute encephalopathy with biphasic seizures and late reduced diffusion associated with Streptococcus sanguinis sepsis |
| title_short | Acute encephalopathy with biphasic seizures and late reduced diffusion associated with Streptococcus sanguinis sepsis |
| title_sort | acute encephalopathy with biphasic seizures and late reduced diffusion associated with streptococcus sanguinis sepsis |
| topic | Acute encephalopathy with biphasic seizures and reduced diffusion, AESD, spinal muscular atrophy, Streptococcus sanguinis, sepsis |
| url | http://www.pagepress.org/journals/index.php/pr/article/view/7424 |
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