Protective effect of chitosan-modified rice porous starch loaded catechin on HT-29 cells exposed to lead ion
Objective: To explore how chitosan-modified rice porous starch-loaded catechin (CT@RPS/CS) protects HT-29 cells exposed to lead ions. Method: The HT-29 cells were treated differently based on their grouping. The effect of CT@RPS/CS on lead-induced toxicity was evaluated using cell proliferation, apo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024010508 |
| _version_ | 1797328605088317440 |
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| author | Suwei Jiang Hailiang Hu |
| author_facet | Suwei Jiang Hailiang Hu |
| author_sort | Suwei Jiang |
| collection | DOAJ |
| description | Objective: To explore how chitosan-modified rice porous starch-loaded catechin (CT@RPS/CS) protects HT-29 cells exposed to lead ions. Method: The HT-29 cells were treated differently based on their grouping. The effect of CT@RPS/CS on lead-induced toxicity was evaluated using cell proliferation, apoptosis, oxidative stress index, and cytokine tests. Results: CT@RPS/CS did not affect the activity, cell apoptosis, oxidative stress level, and related cytokines of HT-29 cells. After exposure to lead, CT@RPS/CS has the potential to enhance cellular activity, minimize apoptosis, and decrease the level of oxidative stress. Discussion: CT@RPS/CS not only has no toxicity to cells but also adsorbs lead ions, which protects cells. |
| first_indexed | 2024-03-08T06:54:06Z |
| format | Article |
| id | doaj.art-819fa64f95b04a408fd33dd2a9083c16 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-08T06:54:06Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-819fa64f95b04a408fd33dd2a9083c162024-02-03T06:38:49ZengElsevierHeliyon2405-84402024-01-01102e25019Protective effect of chitosan-modified rice porous starch loaded catechin on HT-29 cells exposed to lead ionSuwei Jiang0Hailiang Hu1Suwei Jiang, School of Biological, Food and Environmental, Hefei University, Hefei, 230601, Anhui, ChinaHailiang Hu, Department of Blood Transfusion, First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China; Corresponding author.Objective: To explore how chitosan-modified rice porous starch-loaded catechin (CT@RPS/CS) protects HT-29 cells exposed to lead ions. Method: The HT-29 cells were treated differently based on their grouping. The effect of CT@RPS/CS on lead-induced toxicity was evaluated using cell proliferation, apoptosis, oxidative stress index, and cytokine tests. Results: CT@RPS/CS did not affect the activity, cell apoptosis, oxidative stress level, and related cytokines of HT-29 cells. After exposure to lead, CT@RPS/CS has the potential to enhance cellular activity, minimize apoptosis, and decrease the level of oxidative stress. Discussion: CT@RPS/CS not only has no toxicity to cells but also adsorbs lead ions, which protects cells.http://www.sciencedirect.com/science/article/pii/S2405844024010508Porous starchChitosanCatechinAdsorberLead ions |
| spellingShingle | Suwei Jiang Hailiang Hu Protective effect of chitosan-modified rice porous starch loaded catechin on HT-29 cells exposed to lead ion Heliyon Porous starch Chitosan Catechin Adsorber Lead ions |
| title | Protective effect of chitosan-modified rice porous starch loaded catechin on HT-29 cells exposed to lead ion |
| title_full | Protective effect of chitosan-modified rice porous starch loaded catechin on HT-29 cells exposed to lead ion |
| title_fullStr | Protective effect of chitosan-modified rice porous starch loaded catechin on HT-29 cells exposed to lead ion |
| title_full_unstemmed | Protective effect of chitosan-modified rice porous starch loaded catechin on HT-29 cells exposed to lead ion |
| title_short | Protective effect of chitosan-modified rice porous starch loaded catechin on HT-29 cells exposed to lead ion |
| title_sort | protective effect of chitosan modified rice porous starch loaded catechin on ht 29 cells exposed to lead ion |
| topic | Porous starch Chitosan Catechin Adsorber Lead ions |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024010508 |
| work_keys_str_mv | AT suweijiang protectiveeffectofchitosanmodifiedriceporousstarchloadedcatechinonht29cellsexposedtoleadion AT hailianghu protectiveeffectofchitosanmodifiedriceporousstarchloadedcatechinonht29cellsexposedtoleadion |