Clinical characteristics of patients with Ochrobactrum anthropi bloodstream infection in a Chinese tertiary-care hospital: A 7-year study
Background: Ochrobactrum anthropi has become an emerging pathogen for bloodstream infection (BSI). Methods: From January 1st 2010 to June 30th 2017, inpatients with one or more blood cultures positive for O. anthropi isolates at Chinese People’s Liberation Army General Hospital in Beijing, China, we...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-11-01
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| Series: | Journal of Infection and Public Health |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1876034118301138 |
| _version_ | 1818887343858253824 |
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| author | Minghui Zhu Xiaoyan Zhao Qiang Zhu Zhaorui Zhang Yu Dai Liangan Chen Zhixin Liang |
| author_facet | Minghui Zhu Xiaoyan Zhao Qiang Zhu Zhaorui Zhang Yu Dai Liangan Chen Zhixin Liang |
| author_sort | Minghui Zhu |
| collection | DOAJ |
| description | Background: Ochrobactrum anthropi has become an emerging pathogen for bloodstream infection (BSI). Methods: From January 1st 2010 to June 30th 2017, inpatients with one or more blood cultures positive for O. anthropi isolates at Chinese People’s Liberation Army General Hospital in Beijing, China, were enrolled in this study. Clinical and laboratory data were collected by reviewing electronic records. Results: A total of 11 patients with O. anthropi BSI were identified, of which 10 patients survived. There were 6 males and 5 females, whose age ranged from 2 to 83 years. 7 infections were hospital-acquired. In 8 cases O. anthropi was the only pathogen. The most common symptoms of O. anthropi BSI were fever (100%) and disorders of consciousness (45.5%). All patients had undergone indwelling catheter placement. O. anthropi isolates in this study were most susceptible to levofloxacin (100%), ciprofloxacin (85.7%), imipenem (85.7%) and cotrimoxazole (85.7%), while they were widely resistant to penicillins and cephalosporins. Conclusions: O. anthropi BSI usually happens in patients with indwelling catheters, and often begins with no distinctive symptom or laboratory finding. O. anthropi seldom form polymicrobial BSIs. Quinolones and carbapenems are optimal antibiotics for O. anthropi BSI. Catheter removal is essential when O. anthropi BSI happens recurrently. Keywords: Ochrobactrum anthropi, Bloodstream infection, Clinical characteristics, Antimicrobial susceptibility test |
| first_indexed | 2024-12-19T16:35:44Z |
| format | Article |
| id | doaj.art-81a0821cf327462fa81b79442c3f4bfe |
| institution | Directory Open Access Journal |
| issn | 1876-0341 |
| language | English |
| last_indexed | 2024-12-19T16:35:44Z |
| publishDate | 2018-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Infection and Public Health |
| spelling | doaj.art-81a0821cf327462fa81b79442c3f4bfe2022-12-21T20:13:59ZengElsevierJournal of Infection and Public Health1876-03412018-11-01116873877Clinical characteristics of patients with Ochrobactrum anthropi bloodstream infection in a Chinese tertiary-care hospital: A 7-year studyMinghui Zhu0Xiaoyan Zhao1Qiang Zhu2Zhaorui Zhang3Yu Dai4Liangan Chen5Zhixin Liang6Department of Respiratory Medicine, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Respiratory Medicine, The 5th Hospital of PLA, Yinchuan, Ningxia 750004, ChinaDepartment of Respiratory Medicine, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Respiratory Medicine, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Respiratory Medicine, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Respiratory Medicine, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Respiratory Medicine, Chinese PLA General Hospital, Beijing 100853, China; Corresponding author.Background: Ochrobactrum anthropi has become an emerging pathogen for bloodstream infection (BSI). Methods: From January 1st 2010 to June 30th 2017, inpatients with one or more blood cultures positive for O. anthropi isolates at Chinese People’s Liberation Army General Hospital in Beijing, China, were enrolled in this study. Clinical and laboratory data were collected by reviewing electronic records. Results: A total of 11 patients with O. anthropi BSI were identified, of which 10 patients survived. There were 6 males and 5 females, whose age ranged from 2 to 83 years. 7 infections were hospital-acquired. In 8 cases O. anthropi was the only pathogen. The most common symptoms of O. anthropi BSI were fever (100%) and disorders of consciousness (45.5%). All patients had undergone indwelling catheter placement. O. anthropi isolates in this study were most susceptible to levofloxacin (100%), ciprofloxacin (85.7%), imipenem (85.7%) and cotrimoxazole (85.7%), while they were widely resistant to penicillins and cephalosporins. Conclusions: O. anthropi BSI usually happens in patients with indwelling catheters, and often begins with no distinctive symptom or laboratory finding. O. anthropi seldom form polymicrobial BSIs. Quinolones and carbapenems are optimal antibiotics for O. anthropi BSI. Catheter removal is essential when O. anthropi BSI happens recurrently. Keywords: Ochrobactrum anthropi, Bloodstream infection, Clinical characteristics, Antimicrobial susceptibility testhttp://www.sciencedirect.com/science/article/pii/S1876034118301138 |
| spellingShingle | Minghui Zhu Xiaoyan Zhao Qiang Zhu Zhaorui Zhang Yu Dai Liangan Chen Zhixin Liang Clinical characteristics of patients with Ochrobactrum anthropi bloodstream infection in a Chinese tertiary-care hospital: A 7-year study Journal of Infection and Public Health |
| title | Clinical characteristics of patients with Ochrobactrum anthropi bloodstream infection in a Chinese tertiary-care hospital: A 7-year study |
| title_full | Clinical characteristics of patients with Ochrobactrum anthropi bloodstream infection in a Chinese tertiary-care hospital: A 7-year study |
| title_fullStr | Clinical characteristics of patients with Ochrobactrum anthropi bloodstream infection in a Chinese tertiary-care hospital: A 7-year study |
| title_full_unstemmed | Clinical characteristics of patients with Ochrobactrum anthropi bloodstream infection in a Chinese tertiary-care hospital: A 7-year study |
| title_short | Clinical characteristics of patients with Ochrobactrum anthropi bloodstream infection in a Chinese tertiary-care hospital: A 7-year study |
| title_sort | clinical characteristics of patients with ochrobactrum anthropi bloodstream infection in a chinese tertiary care hospital a 7 year study |
| url | http://www.sciencedirect.com/science/article/pii/S1876034118301138 |
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