Identification and validation of a small molecule targeting ROR1 for the treatment of triple negative breast cancer

Identification and validation of a small molecule targeting ROR1 for the treatment of triple negative breast cancer

Introduction: Breast cancer is the most common cancer in women, with roughly 10–15% of new cases classified as triple-negative breast cancer (TNBC). Traditional chemotherapies are often toxic to normal cells. Therefore, it is important to discover new anticancer compounds that target TNBC while caus...

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Bibliographic Details
Main Authors:	Shradheya R. R. Gupta, Tram M. Ta, Maryam Khan, Archana Singh, Indrakant K. Singh, Bela Peethambaran
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-09-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	breast cancer TNBC Ror1 kinase MCF-10A MDA-MB-231
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2023.1243763/full

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