Adenovirus pneumonia mimicking osimertinib‐induced pneumonitis in a patient with advanced NSCLC with EGFR mutation: A case report
Abstract Drug‐related pneumonitis (DRP) caused by epidermal growth factor receptor (EGFR)‐tyrosine kinase inhibitors (TKIs) is a fatal adverse event in patients with EGFR‐mutant non‐small cell lung cancer (NSCLC). The diagnosis of DRP is based on radiological findings, the temporal association of pr...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-03-01
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| Series: | Thoracic Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/1759-7714.15250 |
| _version_ | 1827309852602400768 |
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| author | Toru Imai Tatsuya Yoshida Yuichiro Ohe |
| author_facet | Toru Imai Tatsuya Yoshida Yuichiro Ohe |
| author_sort | Toru Imai |
| collection | DOAJ |
| description | Abstract Drug‐related pneumonitis (DRP) caused by epidermal growth factor receptor (EGFR)‐tyrosine kinase inhibitors (TKIs) is a fatal adverse event in patients with EGFR‐mutant non‐small cell lung cancer (NSCLC). The diagnosis of DRP is based on radiological findings, the temporal association of presentation with the initiation of a systemic therapeutic agent, and the exclusion of other likely causes. Here we report a case in which severe adenoviral pneumonia mimicking DRP occurred during treatment with osimertinib, and osimertinib was successfully resumed after recovery from adenoviral pneumonia. |
| first_indexed | 2024-04-24T19:49:36Z |
| format | Article |
| id | doaj.art-81a6ad46bec84778b4b230dd4c7a3e5b |
| institution | Directory Open Access Journal |
| issn | 1759-7706 1759-7714 |
| language | English |
| last_indexed | 2024-04-24T19:49:36Z |
| publishDate | 2024-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Thoracic Cancer |
| spelling | doaj.art-81a6ad46bec84778b4b230dd4c7a3e5b2024-03-25T01:41:29ZengWileyThoracic Cancer1759-77061759-77142024-03-0115974975110.1111/1759-7714.15250Adenovirus pneumonia mimicking osimertinib‐induced pneumonitis in a patient with advanced NSCLC with EGFR mutation: A case reportToru Imai0Tatsuya Yoshida1Yuichiro Ohe2Department of Thoracic Oncology National Cancer Center Hospital Tokyo JapanDepartment of Thoracic Oncology National Cancer Center Hospital Tokyo JapanDepartment of Thoracic Oncology National Cancer Center Hospital Tokyo JapanAbstract Drug‐related pneumonitis (DRP) caused by epidermal growth factor receptor (EGFR)‐tyrosine kinase inhibitors (TKIs) is a fatal adverse event in patients with EGFR‐mutant non‐small cell lung cancer (NSCLC). The diagnosis of DRP is based on radiological findings, the temporal association of presentation with the initiation of a systemic therapeutic agent, and the exclusion of other likely causes. Here we report a case in which severe adenoviral pneumonia mimicking DRP occurred during treatment with osimertinib, and osimertinib was successfully resumed after recovery from adenoviral pneumonia.https://doi.org/10.1111/1759-7714.15250adenovirus pneumoniadrug‐related pneumonitisosimertinib |
| spellingShingle | Toru Imai Tatsuya Yoshida Yuichiro Ohe Adenovirus pneumonia mimicking osimertinib‐induced pneumonitis in a patient with advanced NSCLC with EGFR mutation: A case report Thoracic Cancer adenovirus pneumonia drug‐related pneumonitis osimertinib |
| title | Adenovirus pneumonia mimicking osimertinib‐induced pneumonitis in a patient with advanced NSCLC with EGFR mutation: A case report |
| title_full | Adenovirus pneumonia mimicking osimertinib‐induced pneumonitis in a patient with advanced NSCLC with EGFR mutation: A case report |
| title_fullStr | Adenovirus pneumonia mimicking osimertinib‐induced pneumonitis in a patient with advanced NSCLC with EGFR mutation: A case report |
| title_full_unstemmed | Adenovirus pneumonia mimicking osimertinib‐induced pneumonitis in a patient with advanced NSCLC with EGFR mutation: A case report |
| title_short | Adenovirus pneumonia mimicking osimertinib‐induced pneumonitis in a patient with advanced NSCLC with EGFR mutation: A case report |
| title_sort | adenovirus pneumonia mimicking osimertinib induced pneumonitis in a patient with advanced nsclc with egfr mutation a case report |
| topic | adenovirus pneumonia drug‐related pneumonitis osimertinib |
| url | https://doi.org/10.1111/1759-7714.15250 |
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