Experimental Comparison of Photothermal Conversion Efficiency of Gold Nanotriangle and Nanorod in Laser Induced Thermal Therapy
An experimental comparison of the photothermal conversion efficiency (PCE) for gold nanotriangles (GNTs) and nanorods (GNRs) was carried out in the present work. The discrete dipole approximation method was applied to identify the spectral characteristic of GNTs and GNRs with different aspect ratios...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-11-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/7/12/416 |
| _version_ | 1811229719104847872 |
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| author | Qin Chen Qin Chen Hong Qi Liming Ruan Yatao Ren |
| author_facet | Qin Chen Qin Chen Hong Qi Liming Ruan Yatao Ren |
| author_sort | Qin Chen |
| collection | DOAJ |
| description | An experimental comparison of the photothermal conversion efficiency (PCE) for gold nanotriangles (GNTs) and nanorods (GNRs) was carried out in the present work. The discrete dipole approximation method was applied to identify the spectral characteristic of GNTs and GNRs with different aspect ratios. On this basis, the PCE of GNTs and GNRs in photothermal therapy were compared theoretically. Afterwards, an in vitro experiment was adopted to investigate the thermal effect of porcine muscle induced by laser irradiation, with and without injected GNTs and GNRs. The influences of laser total power, nanoparticle concentration, and nanoparticle type were investigated. It was found that for the commonly-used wavelengths for photothermal therapy, the PCE of GNTs is higher than that of the GNRs. Furthermore, for GNRs loaded in tissue in vitro, high laser power and high concentration of nanoparticles leads to the degeneration and even carbonization of tissue. However, for the GNTs with the same situation (laser power, nanoparticle volume concentration, and heating time), it could lead to the tissue’s evaporation instead of carbonization. |
| first_indexed | 2024-04-12T10:19:13Z |
| format | Article |
| id | doaj.art-81a8822bcab34f57a76a4a3d356db34f |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-04-12T10:19:13Z |
| publishDate | 2017-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-81a8822bcab34f57a76a4a3d356db34f2022-12-22T03:37:08ZengMDPI AGNanomaterials2079-49912017-11-0171241610.3390/nano7120416nano7120416Experimental Comparison of Photothermal Conversion Efficiency of Gold Nanotriangle and Nanorod in Laser Induced Thermal TherapyQin Chen0Qin Chen1Hong QiLiming RuanYatao Ren2These authors contributed equally to this work.These authors contributed equally to this work.These authors contributed equally to this work.An experimental comparison of the photothermal conversion efficiency (PCE) for gold nanotriangles (GNTs) and nanorods (GNRs) was carried out in the present work. The discrete dipole approximation method was applied to identify the spectral characteristic of GNTs and GNRs with different aspect ratios. On this basis, the PCE of GNTs and GNRs in photothermal therapy were compared theoretically. Afterwards, an in vitro experiment was adopted to investigate the thermal effect of porcine muscle induced by laser irradiation, with and without injected GNTs and GNRs. The influences of laser total power, nanoparticle concentration, and nanoparticle type were investigated. It was found that for the commonly-used wavelengths for photothermal therapy, the PCE of GNTs is higher than that of the GNRs. Furthermore, for GNRs loaded in tissue in vitro, high laser power and high concentration of nanoparticles leads to the degeneration and even carbonization of tissue. However, for the GNTs with the same situation (laser power, nanoparticle volume concentration, and heating time), it could lead to the tissue’s evaporation instead of carbonization.https://www.mdpi.com/2079-4991/7/12/416gold nanoparticlephotothermal conversionnanotrianglenanorodphotothermal therapy |
| spellingShingle | Qin Chen Qin Chen Hong Qi Liming Ruan Yatao Ren Experimental Comparison of Photothermal Conversion Efficiency of Gold Nanotriangle and Nanorod in Laser Induced Thermal Therapy Nanomaterials gold nanoparticle photothermal conversion nanotriangle nanorod photothermal therapy |
| title | Experimental Comparison of Photothermal Conversion Efficiency of Gold Nanotriangle and Nanorod in Laser Induced Thermal Therapy |
| title_full | Experimental Comparison of Photothermal Conversion Efficiency of Gold Nanotriangle and Nanorod in Laser Induced Thermal Therapy |
| title_fullStr | Experimental Comparison of Photothermal Conversion Efficiency of Gold Nanotriangle and Nanorod in Laser Induced Thermal Therapy |
| title_full_unstemmed | Experimental Comparison of Photothermal Conversion Efficiency of Gold Nanotriangle and Nanorod in Laser Induced Thermal Therapy |
| title_short | Experimental Comparison of Photothermal Conversion Efficiency of Gold Nanotriangle and Nanorod in Laser Induced Thermal Therapy |
| title_sort | experimental comparison of photothermal conversion efficiency of gold nanotriangle and nanorod in laser induced thermal therapy |
| topic | gold nanoparticle photothermal conversion nanotriangle nanorod photothermal therapy |
| url | https://www.mdpi.com/2079-4991/7/12/416 |
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