COMPARISON OF HEART RATE VARIABILITY ADJUSTED FOR AGE AND HEART RATE IN WOMEN WITH RHEUMATOID ARTHRITIS AND WOMEN WITHOUT RHEUMATIC DISEASES
<p>Aim. To compare the 24-hour indicators of heart rate variability (HRV), adjusted for age and 24-hour average heart rate (HR24) in women with rheumatoid arthritis (RA) and women of the control group.</p><p>Material and methods. Women with RA (n=291) at the age of 20-60 were exami...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Столичная издательская компания
2015-09-01
|
Series: | Рациональная фармакотерапия в кардиологии |
Subjects: | |
Online Access: | http://www.rpcardio.ru/jour/article/view/249 |
_version_ | 1797711795947831296 |
---|---|
author | D. S. Novikova T. V. Popkova A. N. Gerasimov A. V. Volkov E. I. Nasonov |
author_facet | D. S. Novikova T. V. Popkova A. N. Gerasimov A. V. Volkov E. I. Nasonov |
author_sort | D. S. Novikova |
collection | DOAJ |
description | <p>Aim. To compare the 24-hour indicators of heart rate variability (HRV), adjusted for age and 24-hour average heart rate (HR24) in women with rheumatoid arthritis (RA) and women of the control group.</p><p>Material and methods. Women with RA (n=291) at the age of 20-60 were examined. Women without rheumatic diseases (n=125) were included into control group. The presence of traditional cardiovascular risk factors, the results of 24-hour ECG monitoring were assessed in addition to clinical symptoms, RA activity and severity. Transformation of the initial HRV parameters in their logarithms, and the standardization of the logarithms of age and HR24, the calculation of the exponential of the standardized logarithm were performed to remove the effects of age and heart rate on HRV.</p><p>Results. Time and frequency HRV indices, adjusted for age and HP24 (HRVa) in women with RA were lower than these in women of control group. HRVa decline was observed in 14–24% of women with RA. The maximum HRVa decrease was observed among the parameters that reflect an activity of parasympathetic autonomic nervous system (RMSSDn, pNN50n, HFn).</p><p>Conclusion. The young and middle age women with RA differ from the women of the control group in significant decrease in the time and spectral HRV indices adjusted for age and HR24.</p> |
first_indexed | 2024-03-12T07:12:17Z |
format | Article |
id | doaj.art-81ab456cf3a6478798121f7930574ffd |
institution | Directory Open Access Journal |
issn | 1819-6446 2225-3653 |
language | English |
last_indexed | 2024-03-12T07:12:17Z |
publishDate | 2015-09-01 |
publisher | Столичная издательская компания |
record_format | Article |
series | Рациональная фармакотерапия в кардиологии |
spelling | doaj.art-81ab456cf3a6478798121f7930574ffd2023-09-02T23:01:54ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-09-019212713210.1234/1819-6446-2013-2-127-132249COMPARISON OF HEART RATE VARIABILITY ADJUSTED FOR AGE AND HEART RATE IN WOMEN WITH RHEUMATOID ARTHRITIS AND WOMEN WITHOUT RHEUMATIC DISEASESD. S. Novikova0T. V. Popkova1A. N. Gerasimov2A. V. Volkov3E. I. Nasonov4Научно-исследовательский институт ревматологии, МоскваНаучно-исследовательский институт ревматологии, МоскваПервый Московский государственный медицинский университет имени И.М. СеченоваНаучно-исследовательский институт ревматологии, МоскваНаучно-исследовательский институт ревматологии, Москва<p>Aim. To compare the 24-hour indicators of heart rate variability (HRV), adjusted for age and 24-hour average heart rate (HR24) in women with rheumatoid arthritis (RA) and women of the control group.</p><p>Material and methods. Women with RA (n=291) at the age of 20-60 were examined. Women without rheumatic diseases (n=125) were included into control group. The presence of traditional cardiovascular risk factors, the results of 24-hour ECG monitoring were assessed in addition to clinical symptoms, RA activity and severity. Transformation of the initial HRV parameters in their logarithms, and the standardization of the logarithms of age and HR24, the calculation of the exponential of the standardized logarithm were performed to remove the effects of age and heart rate on HRV.</p><p>Results. Time and frequency HRV indices, adjusted for age and HP24 (HRVa) in women with RA were lower than these in women of control group. HRVa decline was observed in 14–24% of women with RA. The maximum HRVa decrease was observed among the parameters that reflect an activity of parasympathetic autonomic nervous system (RMSSDn, pNN50n, HFn).</p><p>Conclusion. The young and middle age women with RA differ from the women of the control group in significant decrease in the time and spectral HRV indices adjusted for age and HR24.</p>http://www.rpcardio.ru/jour/article/view/249ревматоидный артритвариабельность ритма сердца |
spellingShingle | D. S. Novikova T. V. Popkova A. N. Gerasimov A. V. Volkov E. I. Nasonov COMPARISON OF HEART RATE VARIABILITY ADJUSTED FOR AGE AND HEART RATE IN WOMEN WITH RHEUMATOID ARTHRITIS AND WOMEN WITHOUT RHEUMATIC DISEASES Рациональная фармакотерапия в кардиологии ревматоидный артрит вариабельность ритма сердца |
title | COMPARISON OF HEART RATE VARIABILITY ADJUSTED FOR AGE AND HEART RATE IN WOMEN WITH RHEUMATOID ARTHRITIS AND WOMEN WITHOUT RHEUMATIC DISEASES |
title_full | COMPARISON OF HEART RATE VARIABILITY ADJUSTED FOR AGE AND HEART RATE IN WOMEN WITH RHEUMATOID ARTHRITIS AND WOMEN WITHOUT RHEUMATIC DISEASES |
title_fullStr | COMPARISON OF HEART RATE VARIABILITY ADJUSTED FOR AGE AND HEART RATE IN WOMEN WITH RHEUMATOID ARTHRITIS AND WOMEN WITHOUT RHEUMATIC DISEASES |
title_full_unstemmed | COMPARISON OF HEART RATE VARIABILITY ADJUSTED FOR AGE AND HEART RATE IN WOMEN WITH RHEUMATOID ARTHRITIS AND WOMEN WITHOUT RHEUMATIC DISEASES |
title_short | COMPARISON OF HEART RATE VARIABILITY ADJUSTED FOR AGE AND HEART RATE IN WOMEN WITH RHEUMATOID ARTHRITIS AND WOMEN WITHOUT RHEUMATIC DISEASES |
title_sort | comparison of heart rate variability adjusted for age and heart rate in women with rheumatoid arthritis and women without rheumatic diseases |
topic | ревматоидный артрит вариабельность ритма сердца |
url | http://www.rpcardio.ru/jour/article/view/249 |
work_keys_str_mv | AT dsnovikova comparisonofheartratevariabilityadjustedforageandheartrateinwomenwithrheumatoidarthritisandwomenwithoutrheumaticdiseases AT tvpopkova comparisonofheartratevariabilityadjustedforageandheartrateinwomenwithrheumatoidarthritisandwomenwithoutrheumaticdiseases AT angerasimov comparisonofheartratevariabilityadjustedforageandheartrateinwomenwithrheumatoidarthritisandwomenwithoutrheumaticdiseases AT avvolkov comparisonofheartratevariabilityadjustedforageandheartrateinwomenwithrheumatoidarthritisandwomenwithoutrheumaticdiseases AT einasonov comparisonofheartratevariabilityadjustedforageandheartrateinwomenwithrheumatoidarthritisandwomenwithoutrheumaticdiseases |