Lumbar puncture in patients using anticoagulants and antiplatelet agents
ABSTRACT The use of anticoagulants and antiplatelet agents has largely increased. Diagnostic lumbar puncture in patients taking these drugs represents a challenge considering the opposing risks of bleeding and thrombotic complications. To date there are no controlled trials, specific guidelines, nor...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Academia Brasileira de Neurologia (ABNEURO)
2016-08-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000800679&lng=en&tlng=en |
| _version_ | 1819088002626879488 |
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| author | Renan Domingues Gustavo Bruniera Fernando Brunale Cristóvão Mangueira Carlos Senne |
| author_facet | Renan Domingues Gustavo Bruniera Fernando Brunale Cristóvão Mangueira Carlos Senne |
| author_sort | Renan Domingues |
| collection | DOAJ |
| description | ABSTRACT The use of anticoagulants and antiplatelet agents has largely increased. Diagnostic lumbar puncture in patients taking these drugs represents a challenge considering the opposing risks of bleeding and thrombotic complications. To date there are no controlled trials, specific guidelines, nor clear recommendations in this area. In the present review we make some recommendations about lumbar puncture in patients using these drugs. Our recommendations take into consideration the pharmacology of these drugs, the thrombotic risk according to the underlying disease, and the urgency in cerebrospinal fluid analysis. Evaluating such information and a rigorous monitoring of neurological symptoms after lumbar puncture are crucial to minimize the risk of hemorrhage associated neurological deficits. An individualized patient decision-making and an effective communication between the assistant physician and the responsible for conducting the lumbar puncture are essential to minimize potential risks. |
| first_indexed | 2024-12-21T21:45:07Z |
| format | Article |
| id | doaj.art-81aeaf87f3d14dad943cdc49a3de3387 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-21T21:45:07Z |
| publishDate | 2016-08-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-81aeaf87f3d14dad943cdc49a3de33872022-12-21T18:49:16ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272016-08-0174867968610.1590/0004-282X20160098S0004-282X2016000800679Lumbar puncture in patients using anticoagulants and antiplatelet agentsRenan DominguesGustavo BrunieraFernando BrunaleCristóvão MangueiraCarlos SenneABSTRACT The use of anticoagulants and antiplatelet agents has largely increased. Diagnostic lumbar puncture in patients taking these drugs represents a challenge considering the opposing risks of bleeding and thrombotic complications. To date there are no controlled trials, specific guidelines, nor clear recommendations in this area. In the present review we make some recommendations about lumbar puncture in patients using these drugs. Our recommendations take into consideration the pharmacology of these drugs, the thrombotic risk according to the underlying disease, and the urgency in cerebrospinal fluid analysis. Evaluating such information and a rigorous monitoring of neurological symptoms after lumbar puncture are crucial to minimize the risk of hemorrhage associated neurological deficits. An individualized patient decision-making and an effective communication between the assistant physician and the responsible for conducting the lumbar puncture are essential to minimize potential risks.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000800679&lng=en&tlng=enanticoagulantesinibidores da agregação de plaquetaspunção espinalhematoma espinhal |
| spellingShingle | Renan Domingues Gustavo Bruniera Fernando Brunale Cristóvão Mangueira Carlos Senne Lumbar puncture in patients using anticoagulants and antiplatelet agents Arquivos de Neuro-Psiquiatria anticoagulantes inibidores da agregação de plaquetas punção espinal hematoma espinhal |
| title | Lumbar puncture in patients using anticoagulants and antiplatelet agents |
| title_full | Lumbar puncture in patients using anticoagulants and antiplatelet agents |
| title_fullStr | Lumbar puncture in patients using anticoagulants and antiplatelet agents |
| title_full_unstemmed | Lumbar puncture in patients using anticoagulants and antiplatelet agents |
| title_short | Lumbar puncture in patients using anticoagulants and antiplatelet agents |
| title_sort | lumbar puncture in patients using anticoagulants and antiplatelet agents |
| topic | anticoagulantes inibidores da agregação de plaquetas punção espinal hematoma espinhal |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000800679&lng=en&tlng=en |
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