Altered Th17/Treg Ratio in Peripheral Blood of Systemic Lupus Erythematosus but Not Primary Antiphospholipid Syndrome

Altered Th17/Treg Ratio in Peripheral Blood of Systemic Lupus Erythematosus but Not Primary Antiphospholipid Syndrome

Introduction: The role of the immune response in the pathogenesis of antiphospholipid syndrome (APS) remains elusive. It is possible that differences in the frequencies of Th17 cells and/or defects in the immunoregulatory mechanisms are involved in the pathogenesis of APS. Our aim was to determine t...

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Bibliographic Details
Main Authors: Lorena Álvarez-Rodríguez, Víctor Martínez-Taboada, Jaime Calvo-Alén, Iñaki Beares, Ignacio Villa, Marcos López-Hoyos
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
pAPS
SLE
Th1
Th17
Treg
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00391/full

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