THE PECULIARITIES OF CEREBRAL BLOOD FLOW IN PATIENTS WITH CHRONIC HEPATITIS

<p><strong>Aim.</strong> To study extra- and intracranial hemodynamics in patients with chronic hepatitis of different activity.</p><p><strong>Material and methods.</strong> Ultrasonography of the cerebral blood flow was performed in 576 patients with chroni...

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Bibliographic Details
Main Authors: V. E. Kulikov, B. B. Fishman, A. V. Volkov, G. S. Malyutin, G. I. Shvartsman
Format: Article
Language:English
Published: Столичная издательская компания 2015-12-01
Series:Рациональная фармакотерапия в кардиологии
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Online Access:http://www.rpcardio.ru/jour/article/view/508
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Summary:<p><strong>Aim.</strong> To study extra- and intracranial hemodynamics in patients with chronic hepatitis of different activity.</p><p><strong>Material and methods.</strong> Ultrasonography of the cerebral blood flow was performed in 576 patients with chronic hepatitis.</p><p><strong>Results.</strong> Contralateral hemyspherical asymmetry (more than 30 %) of the maximum linear rate of blood flow in the medium cerebral arteries and decrease in resistance index (0,55±0,09) and pulsativity index (1,34±0,66) were found in 33,8 % of patients with chronic hepatitis of high activity. Collateral blood flow reduction through connecting arteries of Willis circle was revealed in 13,8 % of patients. The tortuosity of arteries and thickening of intima-media complex was found in patients with chronic hepatitis (mainly of high activity). It leads to decline of cerebral blood flow.</p><p><strong>Conclusion.</strong> Symptomatic and asymptomatic cerebral blood flow disturbances were observed in 23,2% and 38,8% of patients with active chronic hepatitis respectively.</p>
ISSN:1819-6446
2225-3653