Rooibos Flavonoids, Aspalathin, Isoorientin, and Orientin Ameliorate Antimycin A-Induced Mitochondrial Dysfunction by Improving Mitochondrial Bioenergetics in Cultured Skeletal Muscle Cells

Rooibos Flavonoids, Aspalathin, Isoorientin, and Orientin Ameliorate Antimycin A-Induced Mitochondrial Dysfunction by Improving Mitochondrial Bioenergetics in Cultured Skeletal Muscle Cells

The current study investigated the physiological effects of flavonoids found in daily consumed rooibos tea, aspalathin, isoorientin, and orientin on improving processes involved in mitochondrial function in C2C12 myotubes. To achieve this, C2C12 myotubes were exposed to a mitochondrial channel block...

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Bibliographic Details
Main Authors: Sinenhlanhla X. H. Mthembu, Christo J. F. Muller, Phiwayinkosi V. Dludla, Evelyn Madoroba, Abidemi P. Kappo, Sithandiwe E. Mazibuko-Mbeje
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
antimycin A
mitochondrial dysfunction
skeletal muscle
isoorientin
orientin
aspalathin
Online Access:https://www.mdpi.com/1420-3049/26/20/6289

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