Inhibition of Period Gene Expression Causes Repression of Cell Cycle Progression and Cell Growth in the Bombyx mori Cells

Inhibition of Period Gene Expression Causes Repression of Cell Cycle Progression and Cell Growth in the Bombyx mori Cells

Circadian clock system disorders can lead to uncontrolled cell proliferation, but the molecular mechanism remains unknown. We used a Bombyx mori animal model of single Period gene (BmPer) expression to investigate this mechanism. A slow growing developmental cell model (Per-KD) was isolated from a B...

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Bibliographic Details
Main Authors: Jian-Feng Qiu, Xue Li, Wen-Zhao Cui, Xiao-Fei Liu, Hui Tao, Kun Yang, Tai-Ming Dai, Yang-Hu Sima, Shi-Qing Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Physiology
Subjects:
Period gene
cell cycle
apoptosis
autophagy
ovarian cell line
Bombyx mori
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00537/full

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