Diversity and Reassortment Rate of Influenza A Viruses in Wild Ducks and Gulls
Influenza A viruses (IAVs) evolve via point mutations and reassortment of viral gene segments. The patterns of reassortment in different host species differ considerably. We investigated the genetic diversity of IAVs in wild ducks and compared it with the viral diversity in gulls. The complete genom...
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| Format: | Article |
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/13/6/1010 |
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| author | Yulia Postnikova Anastasia Treshchalina Elizaveta Boravleva Alexandra Gambaryan Aydar Ishmukhametov Mikhail Matrosovich Ron A. M. Fouchier Galina Sadykova Alexey Prilipov Natalia Lomakina |
| author_facet | Yulia Postnikova Anastasia Treshchalina Elizaveta Boravleva Alexandra Gambaryan Aydar Ishmukhametov Mikhail Matrosovich Ron A. M. Fouchier Galina Sadykova Alexey Prilipov Natalia Lomakina |
| author_sort | Yulia Postnikova |
| collection | DOAJ |
| description | Influenza A viruses (IAVs) evolve via point mutations and reassortment of viral gene segments. The patterns of reassortment in different host species differ considerably. We investigated the genetic diversity of IAVs in wild ducks and compared it with the viral diversity in gulls. The complete genomes of 38 IAVs of H1N1, H1N2, H3N1, H3N2, H3N6, H3N8, H4N6, H5N3, H6N2, H11N6, and H11N9 subtypes isolated from wild mallard ducks and gulls resting in a city pond in Moscow, Russia were sequenced. The analysis of phylogenetic trees showed that stable viral genotypes do not persist from year to year in ducks owing to frequent gene reassortment. For comparison, similar analyses were carried out using sequences of IAVs isolated in the same period from ducks and gulls in The Netherlands. Our results revealed a significant difference in diversity and rates of reassortment of IAVs in ducks and gulls. |
| first_indexed | 2024-03-10T10:57:37Z |
| format | Article |
| id | doaj.art-81b311b9654349daae901f2cb1721522 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T10:57:37Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-81b311b9654349daae901f2cb17215222023-11-21T21:43:49ZengMDPI AGViruses1999-49152021-05-01136101010.3390/v13061010Diversity and Reassortment Rate of Influenza A Viruses in Wild Ducks and GullsYulia Postnikova0Anastasia Treshchalina1Elizaveta Boravleva2Alexandra Gambaryan3Aydar Ishmukhametov4Mikhail Matrosovich5Ron A. M. Fouchier6Galina Sadykova7Alexey Prilipov8Natalia Lomakina9Chumakov Federal Scientific Center for the Research and Development of Immune-and-Biological Products, Village of Institute of Poliomyelitis, Settlement “Moskovskiy”, 108819 Moscow, RussiaChumakov Federal Scientific Center for the Research and Development of Immune-and-Biological Products, Village of Institute of Poliomyelitis, Settlement “Moskovskiy”, 108819 Moscow, RussiaChumakov Federal Scientific Center for the Research and Development of Immune-and-Biological Products, Village of Institute of Poliomyelitis, Settlement “Moskovskiy”, 108819 Moscow, RussiaChumakov Federal Scientific Center for the Research and Development of Immune-and-Biological Products, Village of Institute of Poliomyelitis, Settlement “Moskovskiy”, 108819 Moscow, RussiaChumakov Federal Scientific Center for the Research and Development of Immune-and-Biological Products, Village of Institute of Poliomyelitis, Settlement “Moskovskiy”, 108819 Moscow, RussiaInstitute of Virology, Philipps University, Hans-Meerwein-Str. 2, D-35043 Marburg, GermanyDepartment of Virology, Erasmus Medical Centre, Dr. Molewaterplein 50, 3015GE Rotterdam, The NetherlandsThe Gamaleya National Center of Epidemiology and Microbiology of the Russian Ministry of Health, 123098 Moscow, RussiaThe Gamaleya National Center of Epidemiology and Microbiology of the Russian Ministry of Health, 123098 Moscow, RussiaThe Gamaleya National Center of Epidemiology and Microbiology of the Russian Ministry of Health, 123098 Moscow, RussiaInfluenza A viruses (IAVs) evolve via point mutations and reassortment of viral gene segments. The patterns of reassortment in different host species differ considerably. We investigated the genetic diversity of IAVs in wild ducks and compared it with the viral diversity in gulls. The complete genomes of 38 IAVs of H1N1, H1N2, H3N1, H3N2, H3N6, H3N8, H4N6, H5N3, H6N2, H11N6, and H11N9 subtypes isolated from wild mallard ducks and gulls resting in a city pond in Moscow, Russia were sequenced. The analysis of phylogenetic trees showed that stable viral genotypes do not persist from year to year in ducks owing to frequent gene reassortment. For comparison, similar analyses were carried out using sequences of IAVs isolated in the same period from ducks and gulls in The Netherlands. Our results revealed a significant difference in diversity and rates of reassortment of IAVs in ducks and gulls.https://www.mdpi.com/1999-4915/13/6/1010avian influenzareassortmentdiversity |
| spellingShingle | Yulia Postnikova Anastasia Treshchalina Elizaveta Boravleva Alexandra Gambaryan Aydar Ishmukhametov Mikhail Matrosovich Ron A. M. Fouchier Galina Sadykova Alexey Prilipov Natalia Lomakina Diversity and Reassortment Rate of Influenza A Viruses in Wild Ducks and Gulls Viruses avian influenza reassortment diversity |
| title | Diversity and Reassortment Rate of Influenza A Viruses in Wild Ducks and Gulls |
| title_full | Diversity and Reassortment Rate of Influenza A Viruses in Wild Ducks and Gulls |
| title_fullStr | Diversity and Reassortment Rate of Influenza A Viruses in Wild Ducks and Gulls |
| title_full_unstemmed | Diversity and Reassortment Rate of Influenza A Viruses in Wild Ducks and Gulls |
| title_short | Diversity and Reassortment Rate of Influenza A Viruses in Wild Ducks and Gulls |
| title_sort | diversity and reassortment rate of influenza a viruses in wild ducks and gulls |
| topic | avian influenza reassortment diversity |
| url | https://www.mdpi.com/1999-4915/13/6/1010 |
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