Mutation of the N-Terminal Region of Chikungunya Virus Capsid Protein: Implications for Vaccine Design
ABSTRACT Mosquito-transmitted chikungunya virus (CHIKV) is an arthritogenic alphavirus of the Togaviridae family responsible for frequent outbreaks of arthritic disease in humans. Capsid protein, a structural protein encoded by the CHIKV RNA genome, is able to translocate to the host cell nucleolus....
Main Authors: | Adam Taylor, Xiang Liu, Ali Zaid, Lucas Y. H. Goh, Jody Hobson-Peters, Roy A. Hall, Andres Merits, Suresh Mahalingam |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-03-01
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Series: | mBio |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.01970-16 |
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