Efficient refolding and functional characterization of PfAMA1(DI+DII) expressed in E. coli

Efficient refolding and functional characterization of PfAMA1(DI+DII) expressed in E. coli

Apical membrane antigen 1 (AMA1) is a surface protein of Plasmodium sp. that plays a crucial role in forming moving junction (MJ) during the invasion of human red blood cells. The obligatory presence of AMA1 in the parasite lifecycle designates this protein as a potential vaccine candidate and an es...

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Bibliographic Details
Main Authors: Anamika Biswas, Sreejith Raran-Kurussi, Akash Narayan, Abhisek Kar, Purna Chandra Mashurabad, Mrinal Kanti Bhattacharyya, Kalyaneswar Mandal
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
PfAMA1
Protein expression
E. coli
Refolding
Protein-protein interactions
Surface plasmon resonance
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821000443

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