Effect of microplastics deposition on human lung airways: A review with computational benefits and challenges
Microplastics have become omnipresent in the environment, including the air we inhale, the water we consume, and the food we eat. Despite limited research, the accumulation of microplastics within the human respiratory system has garnered considerable interest because of its potential implications f...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-01-01
|
| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024003864 |
| _version_ | 1797328672240173056 |
|---|---|
| author | Suvash C. Saha Goutam Saha |
| author_facet | Suvash C. Saha Goutam Saha |
| author_sort | Suvash C. Saha |
| collection | DOAJ |
| description | Microplastics have become omnipresent in the environment, including the air we inhale, the water we consume, and the food we eat. Despite limited research, the accumulation of microplastics within the human respiratory system has garnered considerable interest because of its potential implications for health. This review offers a comprehensive examination of the impacts stemming from the accumulation of microplastics on human lung airways and explores the computational benefits and challenges associated with studying this phenomenon. The existence of microplastics in the respiratory system can lead to a range of adverse effects. Research has indicated that microplastics can induce inflammation, oxidative stress, and impaired lung function. Furthermore, the small size of microplastics allows them to penetrate deep into the lungs, reaching the alveoli, where gas exchange takes place. This raises concerns about long-term health consequences, such as the development of respiratory diseases and the potential for translocation to other organs. Computational approaches have been instrumental in understanding the impact of microplastic deposition on human lung airways. Computational models and simulations enable the investigation of particle dynamics, deposition patterns, and interaction mechanisms at various levels of complexity. However, studying microplastics in the lung airways using computational methods presents several challenges. The complex anatomy and physiological processes of the respiratory system require accurate representation in computational models. Obtaining relevant data for model validation and parameterization remains a significant hurdle. Additionally, the diverse nature of microplastics, including variations in size, shape, and chemical composition, poses challenges in capturing their full range of behaviours and potential toxicological effects. |
| first_indexed | 2024-03-08T06:55:04Z |
| format | Article |
| id | doaj.art-81c0e17e804c4e67b9b44e0bef11a275 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-08T06:55:04Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-81c0e17e804c4e67b9b44e0bef11a2752024-02-03T06:37:05ZengElsevierHeliyon2405-84402024-01-01102e24355Effect of microplastics deposition on human lung airways: A review with computational benefits and challengesSuvash C. Saha0Goutam Saha1School of Mechanical and Mechatronic Engineering, University of Technology Sydney, NSW, 2007, Australia; Corresponding author.Department of Mathematics, University of Dhaka, Dhaka, 1000, BangladeshMicroplastics have become omnipresent in the environment, including the air we inhale, the water we consume, and the food we eat. Despite limited research, the accumulation of microplastics within the human respiratory system has garnered considerable interest because of its potential implications for health. This review offers a comprehensive examination of the impacts stemming from the accumulation of microplastics on human lung airways and explores the computational benefits and challenges associated with studying this phenomenon. The existence of microplastics in the respiratory system can lead to a range of adverse effects. Research has indicated that microplastics can induce inflammation, oxidative stress, and impaired lung function. Furthermore, the small size of microplastics allows them to penetrate deep into the lungs, reaching the alveoli, where gas exchange takes place. This raises concerns about long-term health consequences, such as the development of respiratory diseases and the potential for translocation to other organs. Computational approaches have been instrumental in understanding the impact of microplastic deposition on human lung airways. Computational models and simulations enable the investigation of particle dynamics, deposition patterns, and interaction mechanisms at various levels of complexity. However, studying microplastics in the lung airways using computational methods presents several challenges. The complex anatomy and physiological processes of the respiratory system require accurate representation in computational models. Obtaining relevant data for model validation and parameterization remains a significant hurdle. Additionally, the diverse nature of microplastics, including variations in size, shape, and chemical composition, poses challenges in capturing their full range of behaviours and potential toxicological effects.http://www.sciencedirect.com/science/article/pii/S2405844024003864MicroplasticsLungMicroplastic's size and shapeNanoplasticsCosmeticsEnvironment |
| spellingShingle | Suvash C. Saha Goutam Saha Effect of microplastics deposition on human lung airways: A review with computational benefits and challenges Heliyon Microplastics Lung Microplastic's size and shape Nanoplastics Cosmetics Environment |
| title | Effect of microplastics deposition on human lung airways: A review with computational benefits and challenges |
| title_full | Effect of microplastics deposition on human lung airways: A review with computational benefits and challenges |
| title_fullStr | Effect of microplastics deposition on human lung airways: A review with computational benefits and challenges |
| title_full_unstemmed | Effect of microplastics deposition on human lung airways: A review with computational benefits and challenges |
| title_short | Effect of microplastics deposition on human lung airways: A review with computational benefits and challenges |
| title_sort | effect of microplastics deposition on human lung airways a review with computational benefits and challenges |
| topic | Microplastics Lung Microplastic's size and shape Nanoplastics Cosmetics Environment |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024003864 |
| work_keys_str_mv | AT suvashcsaha effectofmicroplasticsdepositiononhumanlungairwaysareviewwithcomputationalbenefitsandchallenges AT goutamsaha effectofmicroplasticsdepositiononhumanlungairwaysareviewwithcomputationalbenefitsandchallenges |