The cellular and KSHV A-to-I RNA editome in primary effusion lymphoma and its role in the viral lifecycle
The Karijolich laboratory describes an atlas of A-to-I RNA editing during the KSHV lifecycle in primary effusion lymphoma. These analyses identified conserved editing events within a viral-encoded microRNA, revealing a critical role for the microRNA and its modification in virus infection.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-37105-8 |
| _version_ | 1797864223364087808 |
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| author | Suba Rajendren Xiang Ye William Dunker Antiana Richardson John Karijolich |
| author_facet | Suba Rajendren Xiang Ye William Dunker Antiana Richardson John Karijolich |
| author_sort | Suba Rajendren |
| collection | DOAJ |
| description | The Karijolich laboratory describes an atlas of A-to-I RNA editing during the KSHV lifecycle in primary effusion lymphoma. These analyses identified conserved editing events within a viral-encoded microRNA, revealing a critical role for the microRNA and its modification in virus infection. |
| first_indexed | 2024-04-09T22:48:16Z |
| format | Article |
| id | doaj.art-81c5c41ceaa2425ba38aeaa373d4d292 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-09T22:48:16Z |
| publishDate | 2023-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-81c5c41ceaa2425ba38aeaa373d4d2922023-03-22T11:43:30ZengNature PortfolioNature Communications2041-17232023-03-0114111510.1038/s41467-023-37105-8The cellular and KSHV A-to-I RNA editome in primary effusion lymphoma and its role in the viral lifecycleSuba Rajendren0Xiang Ye1William Dunker2Antiana Richardson3John Karijolich4Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical CenterDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical CenterDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical CenterDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical CenterDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical CenterThe Karijolich laboratory describes an atlas of A-to-I RNA editing during the KSHV lifecycle in primary effusion lymphoma. These analyses identified conserved editing events within a viral-encoded microRNA, revealing a critical role for the microRNA and its modification in virus infection.https://doi.org/10.1038/s41467-023-37105-8 |
| spellingShingle | Suba Rajendren Xiang Ye William Dunker Antiana Richardson John Karijolich The cellular and KSHV A-to-I RNA editome in primary effusion lymphoma and its role in the viral lifecycle Nature Communications |
| title | The cellular and KSHV A-to-I RNA editome in primary effusion lymphoma and its role in the viral lifecycle |
| title_full | The cellular and KSHV A-to-I RNA editome in primary effusion lymphoma and its role in the viral lifecycle |
| title_fullStr | The cellular and KSHV A-to-I RNA editome in primary effusion lymphoma and its role in the viral lifecycle |
| title_full_unstemmed | The cellular and KSHV A-to-I RNA editome in primary effusion lymphoma and its role in the viral lifecycle |
| title_short | The cellular and KSHV A-to-I RNA editome in primary effusion lymphoma and its role in the viral lifecycle |
| title_sort | cellular and kshv a to i rna editome in primary effusion lymphoma and its role in the viral lifecycle |
| url | https://doi.org/10.1038/s41467-023-37105-8 |
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