Pathological Basis of Imaging in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is the most prevalent form of liver cancer with major risk factors being chronic liver disease (CLD) including chronic liver inflammation, steatohepatitis and certain viral infections (Hepatitis B and C). Due to the poor prognosis, early detection is key for effective...

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Main Authors: Saugata Sen, Anisha Gehani, Priya Ghosh, Anurima Patra, Sumit Mukhopadhyay, Aditi Chandra, Dayananda Lingegowda, Jeevitesh Khoda, Argha Chatterjee
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2023-09-01
Series:Journal of Gastrointestinal and Abdominal Radiology
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1764310
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author Saugata Sen
Anisha Gehani
Priya Ghosh
Anurima Patra
Sumit Mukhopadhyay
Aditi Chandra
Dayananda Lingegowda
Jeevitesh Khoda
Argha Chatterjee
author_facet Saugata Sen
Anisha Gehani
Priya Ghosh
Anurima Patra
Sumit Mukhopadhyay
Aditi Chandra
Dayananda Lingegowda
Jeevitesh Khoda
Argha Chatterjee
author_sort Saugata Sen
collection DOAJ
description Hepatocellular carcinoma (HCC) is the most prevalent form of liver cancer with major risk factors being chronic liver disease (CLD) including chronic liver inflammation, steatohepatitis and certain viral infections (Hepatitis B and C). Due to the poor prognosis, early detection is key for effective management. Imaging of HCC has developed over the years with specificity as high as 95%. The Liver Imaging Reporting and Data System (LI-RADS) provides a standardized reporting format that can be followed by radiologists and clinicians alike. This article focuses on the pathological basis of imaging observations described in the LI-RADS lexicon. A clear understanding of the pathological basis of imaging will help the radiologist to be more confident to resolve unequivocal observations apart from achieving a high degree of specificity in the diagnosis of HCC.
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spelling doaj.art-81c5f560b00d4bcbb9a35e14733749342023-10-17T22:39:39ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Gastrointestinal and Abdominal Radiology2581-91782023-09-01060316017210.1055/s-0043-1764310Pathological Basis of Imaging in Hepatocellular CarcinomaSaugata Sen0https://orcid.org/0000-0002-0418-712XAnisha Gehani1https://orcid.org/0000-0002-7395-0766Priya Ghosh2Anurima Patra3Sumit Mukhopadhyay4Aditi Chandra5Dayananda Lingegowda6https://orcid.org/0000-0002-4899-9170Jeevitesh Khoda7Argha Chatterjee8https://orcid.org/0000-0001-5570-2737Department of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaHepatocellular carcinoma (HCC) is the most prevalent form of liver cancer with major risk factors being chronic liver disease (CLD) including chronic liver inflammation, steatohepatitis and certain viral infections (Hepatitis B and C). Due to the poor prognosis, early detection is key for effective management. Imaging of HCC has developed over the years with specificity as high as 95%. The Liver Imaging Reporting and Data System (LI-RADS) provides a standardized reporting format that can be followed by radiologists and clinicians alike. This article focuses on the pathological basis of imaging observations described in the LI-RADS lexicon. A clear understanding of the pathological basis of imaging will help the radiologist to be more confident to resolve unequivocal observations apart from achieving a high degree of specificity in the diagnosis of HCC.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1764310computed tomographyhepatocellular carcinomaLiver Imaging Reporting and Data Systemmagnetic resonance imaging
spellingShingle Saugata Sen
Anisha Gehani
Priya Ghosh
Anurima Patra
Sumit Mukhopadhyay
Aditi Chandra
Dayananda Lingegowda
Jeevitesh Khoda
Argha Chatterjee
Pathological Basis of Imaging in Hepatocellular Carcinoma
Journal of Gastrointestinal and Abdominal Radiology
computed tomography
hepatocellular carcinoma
Liver Imaging Reporting and Data System
magnetic resonance imaging
title Pathological Basis of Imaging in Hepatocellular Carcinoma
title_full Pathological Basis of Imaging in Hepatocellular Carcinoma
title_fullStr Pathological Basis of Imaging in Hepatocellular Carcinoma
title_full_unstemmed Pathological Basis of Imaging in Hepatocellular Carcinoma
title_short Pathological Basis of Imaging in Hepatocellular Carcinoma
title_sort pathological basis of imaging in hepatocellular carcinoma
topic computed tomography
hepatocellular carcinoma
Liver Imaging Reporting and Data System
magnetic resonance imaging
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1764310
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AT anurimapatra pathologicalbasisofimaginginhepatocellularcarcinoma
AT sumitmukhopadhyay pathologicalbasisofimaginginhepatocellularcarcinoma
AT aditichandra pathologicalbasisofimaginginhepatocellularcarcinoma
AT dayanandalingegowda pathologicalbasisofimaginginhepatocellularcarcinoma
AT jeeviteshkhoda pathologicalbasisofimaginginhepatocellularcarcinoma
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