Pathological Basis of Imaging in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the most prevalent form of liver cancer with major risk factors being chronic liver disease (CLD) including chronic liver inflammation, steatohepatitis and certain viral infections (Hepatitis B and C). Due to the poor prognosis, early detection is key for effective...
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Format: | Article |
Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2023-09-01
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Series: | Journal of Gastrointestinal and Abdominal Radiology |
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Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1764310 |
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author | Saugata Sen Anisha Gehani Priya Ghosh Anurima Patra Sumit Mukhopadhyay Aditi Chandra Dayananda Lingegowda Jeevitesh Khoda Argha Chatterjee |
author_facet | Saugata Sen Anisha Gehani Priya Ghosh Anurima Patra Sumit Mukhopadhyay Aditi Chandra Dayananda Lingegowda Jeevitesh Khoda Argha Chatterjee |
author_sort | Saugata Sen |
collection | DOAJ |
description | Hepatocellular carcinoma (HCC) is the most prevalent form of liver cancer with major risk factors being chronic liver disease (CLD) including chronic liver inflammation, steatohepatitis and certain viral infections (Hepatitis B and C). Due to the poor prognosis, early detection is key for effective management. Imaging of HCC has developed over the years with specificity as high as 95%. The Liver Imaging Reporting and Data System (LI-RADS) provides a standardized reporting format that can be followed by radiologists and clinicians alike. This article focuses on the pathological basis of imaging observations described in the LI-RADS lexicon. A clear understanding of the pathological basis of imaging will help the radiologist to be more confident to resolve unequivocal observations apart from achieving a high degree of specificity in the diagnosis of HCC. |
first_indexed | 2024-03-11T17:53:12Z |
format | Article |
id | doaj.art-81c5f560b00d4bcbb9a35e1473374934 |
institution | Directory Open Access Journal |
issn | 2581-9178 |
language | English |
last_indexed | 2024-03-11T17:53:12Z |
publishDate | 2023-09-01 |
publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
record_format | Article |
series | Journal of Gastrointestinal and Abdominal Radiology |
spelling | doaj.art-81c5f560b00d4bcbb9a35e14733749342023-10-17T22:39:39ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Gastrointestinal and Abdominal Radiology2581-91782023-09-01060316017210.1055/s-0043-1764310Pathological Basis of Imaging in Hepatocellular CarcinomaSaugata Sen0https://orcid.org/0000-0002-0418-712XAnisha Gehani1https://orcid.org/0000-0002-7395-0766Priya Ghosh2Anurima Patra3Sumit Mukhopadhyay4Aditi Chandra5Dayananda Lingegowda6https://orcid.org/0000-0002-4899-9170Jeevitesh Khoda7Argha Chatterjee8https://orcid.org/0000-0001-5570-2737Department of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaDepartment of Radiology and Imaging Sciences, Tata Medical Center, Newtown, Rajarhat, Kolkata, West Bengal, IndiaHepatocellular carcinoma (HCC) is the most prevalent form of liver cancer with major risk factors being chronic liver disease (CLD) including chronic liver inflammation, steatohepatitis and certain viral infections (Hepatitis B and C). Due to the poor prognosis, early detection is key for effective management. Imaging of HCC has developed over the years with specificity as high as 95%. The Liver Imaging Reporting and Data System (LI-RADS) provides a standardized reporting format that can be followed by radiologists and clinicians alike. This article focuses on the pathological basis of imaging observations described in the LI-RADS lexicon. A clear understanding of the pathological basis of imaging will help the radiologist to be more confident to resolve unequivocal observations apart from achieving a high degree of specificity in the diagnosis of HCC.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1764310computed tomographyhepatocellular carcinomaLiver Imaging Reporting and Data Systemmagnetic resonance imaging |
spellingShingle | Saugata Sen Anisha Gehani Priya Ghosh Anurima Patra Sumit Mukhopadhyay Aditi Chandra Dayananda Lingegowda Jeevitesh Khoda Argha Chatterjee Pathological Basis of Imaging in Hepatocellular Carcinoma Journal of Gastrointestinal and Abdominal Radiology computed tomography hepatocellular carcinoma Liver Imaging Reporting and Data System magnetic resonance imaging |
title | Pathological Basis of Imaging in Hepatocellular Carcinoma |
title_full | Pathological Basis of Imaging in Hepatocellular Carcinoma |
title_fullStr | Pathological Basis of Imaging in Hepatocellular Carcinoma |
title_full_unstemmed | Pathological Basis of Imaging in Hepatocellular Carcinoma |
title_short | Pathological Basis of Imaging in Hepatocellular Carcinoma |
title_sort | pathological basis of imaging in hepatocellular carcinoma |
topic | computed tomography hepatocellular carcinoma Liver Imaging Reporting and Data System magnetic resonance imaging |
url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1764310 |
work_keys_str_mv | AT saugatasen pathologicalbasisofimaginginhepatocellularcarcinoma AT anishagehani pathologicalbasisofimaginginhepatocellularcarcinoma AT priyaghosh pathologicalbasisofimaginginhepatocellularcarcinoma AT anurimapatra pathologicalbasisofimaginginhepatocellularcarcinoma AT sumitmukhopadhyay pathologicalbasisofimaginginhepatocellularcarcinoma AT aditichandra pathologicalbasisofimaginginhepatocellularcarcinoma AT dayanandalingegowda pathologicalbasisofimaginginhepatocellularcarcinoma AT jeeviteshkhoda pathologicalbasisofimaginginhepatocellularcarcinoma AT arghachatterjee pathologicalbasisofimaginginhepatocellularcarcinoma |