miR-184 represses β-catenin and behaves as a skin tumor suppressor
Abstract miR-184-knockout mice display perturbed epidermal stem cell differentiation. However, the potential role of miR-184 in skin pathology is unclear. Here, we report that miR-184 controls epidermal stem cell dynamics and that miR-184 ablation enhances skin carcinogenesis in mice. In agreement,...
Päätekijät: | Lubov Turovsky, Ghazal Kheshaiboun, Gharam Yassen, Sara Nagosa, Ilanit Boyango, Aya Amitai-Lange, Swarnabh Bhattacharya, Neta Ilan, Israel Vlodavsky, Daniel Aberdam, Ruby Shalom-Feuerstein, Emily Avitan-Hersh |
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Aineistotyyppi: | Artikkeli |
Kieli: | English |
Julkaistu: |
Nature Publishing Group
2024-02-01
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Sarja: | Cell Death and Disease |
Linkit: | https://doi.org/10.1038/s41419-024-06554-4 |
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