HOTTIP Predicts Poor Survival in Gastric Cancer Patients and Contributes to Cisplatin Resistance by Sponging miR-216a-5p

HOTTIP Predicts Poor Survival in Gastric Cancer Patients and Contributes to Cisplatin Resistance by Sponging miR-216a-5p

Gastric cancer (GC) is a significant public health burden worldwide, and cisplatin resistance is the leading cause for the failure of chemotherapy in this disease. Previous studies have revealed that HOXA transcript at the distal tip (HOTTIP) is involved in the pathology of GC and is associated with...

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Bibliographic Details
Main Authors: Rui Zhao, Xin Zhang, Yanli Zhang, Yaping Zhang, Yongmei Yang, Yue Sun, Xin Zheng, Ailin Qu, Yvette Umwali, Yi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
gastric cancer
HOTTIP
miR-216a-5p
autophagy
chemoresistance
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00348/full

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