Trends in teicoplanin loading dose implementation from 2010 to 2019 and evaluation of safety and efficacy factors: a retrospective cohort study based on a Japanese administrative claims database

Trends in teicoplanin loading dose implementation from 2010 to 2019 and evaluation of safety and efficacy factors: a retrospective cohort study based on a Japanese administrative claims database

Abstract Background The loading dose of teicoplanin (TEIC) is recommended for implementation. However, there is significant discrepancy between the dose settings in the package insert and, in the guidelines, and the actual status of loading doses in Japan is unclear. Furthermore, TEIC causes liver i...

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Bibliographic Details
Main Authors: Ryota Goto, Yuichi Muraki, Ryo Inose, Moeno Ichii, Keisuke Sawada, Kanako Mizuno, Ryuji Koizumi, Shinya Tsuzuki, Masahiro Ishikane, Norio Ohmagari
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Pharmaceutical Health Care and Sciences
Subjects:
Teicoplanin
Database
Loading dose
Liver injury
Mortality
Methicillin-resistant Staphylococcus aureus
Online Access:https://doi.org/10.1186/s40780-023-00304-y

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