Clinical Application of Thromboelastography in Patients With Severe Fever With Thrombocytopenia Syndrome
Aim To investigate the clinical application of thromboelastography (TEG) in severe fever with thrombocytopenia syndrome (SFTS). Methods One hundred and fifty-seven patients with SFTS were included in the study. The participants were distributed into 3 groups; A, B, and C. And 103 patients in group A...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2023-06-01
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| Series: | Clinical and Applied Thrombosis/Hemostasis |
| Online Access: | https://doi.org/10.1177/10760296231180170 |
| _version_ | 1797802517589917696 |
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| author | Yingbo Li BS Changjuan An MS Peng Xue BS Lina Ni MS Xia Yu BS Jiangli Qu BS Yingjie Yao BS Chengyong Yu BS |
| author_facet | Yingbo Li BS Changjuan An MS Peng Xue BS Lina Ni MS Xia Yu BS Jiangli Qu BS Yingjie Yao BS Chengyong Yu BS |
| author_sort | Yingbo Li BS |
| collection | DOAJ |
| description | Aim To investigate the clinical application of thromboelastography (TEG) in severe fever with thrombocytopenia syndrome (SFTS). Methods One hundred and fifty-seven patients with SFTS were included in the study. The participants were distributed into 3 groups; A, B, and C. And 103 patients in group A met the clinical criteria as they exhibited slight liver and kidney dysfunction. Group B consisted of 54 patients with SFTS who were critically ill while group C was a healthy control group with 58 participants. Results Patients with SFTS exhibited lower coagulation than the healthy participants. Group B patients exhibited significantly lower coagulation compared to group A. There was no significant difference in platelet count and fibrinogen content between patients in group A and group B, but platelet aggregation function and fibrinogen activity were significantly lower in group B patients. Conclusion Our results suggest that it is risky to solely rely on platelet count and the fibrinogen in SFTS. Monitoring of TEG and other coagulation indexes should be emphasized. |
| first_indexed | 2024-03-13T05:06:53Z |
| format | Article |
| id | doaj.art-81cb9183843f4602a27a09a5fbc0f60e |
| institution | Directory Open Access Journal |
| issn | 1938-2723 |
| language | English |
| last_indexed | 2024-03-13T05:06:53Z |
| publishDate | 2023-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical and Applied Thrombosis/Hemostasis |
| spelling | doaj.art-81cb9183843f4602a27a09a5fbc0f60e2023-06-16T08:03:24ZengSAGE PublishingClinical and Applied Thrombosis/Hemostasis1938-27232023-06-012910.1177/10760296231180170Clinical Application of Thromboelastography in Patients With Severe Fever With Thrombocytopenia SyndromeYingbo Li BS0Changjuan An MS1Peng Xue BS2Lina Ni MS3Xia Yu BS4Jiangli Qu BS5Yingjie Yao BS6Chengyong Yu BS7 Department of Blood Transfusion, Central Hospital of Weihai, Weihai, Shandong Province, China Department of Blood Transfusion, Central Hospital of Weihai, Weihai, Shandong Province, China Department of Blood Transfusion, Central Hospital of Weihai, Weihai, Shandong Province, China Department of Blood Transfusion, Central Hospital of Weihai, Weihai, Shandong Province, China Department of Blood Transfusion, Central Hospital of Weihai, Weihai, Shandong Province, China Department of Blood Transfusion, Central Hospital of Weihai, Weihai, Shandong Province, China Department of Blood Transfusion, Central Hospital of Weihai, Weihai, Shandong Province, China Department of Blood Transfusion, Central Hospital of Weihai, Weihai, Shandong Province, ChinaAim To investigate the clinical application of thromboelastography (TEG) in severe fever with thrombocytopenia syndrome (SFTS). Methods One hundred and fifty-seven patients with SFTS were included in the study. The participants were distributed into 3 groups; A, B, and C. And 103 patients in group A met the clinical criteria as they exhibited slight liver and kidney dysfunction. Group B consisted of 54 patients with SFTS who were critically ill while group C was a healthy control group with 58 participants. Results Patients with SFTS exhibited lower coagulation than the healthy participants. Group B patients exhibited significantly lower coagulation compared to group A. There was no significant difference in platelet count and fibrinogen content between patients in group A and group B, but platelet aggregation function and fibrinogen activity were significantly lower in group B patients. Conclusion Our results suggest that it is risky to solely rely on platelet count and the fibrinogen in SFTS. Monitoring of TEG and other coagulation indexes should be emphasized.https://doi.org/10.1177/10760296231180170 |
| spellingShingle | Yingbo Li BS Changjuan An MS Peng Xue BS Lina Ni MS Xia Yu BS Jiangli Qu BS Yingjie Yao BS Chengyong Yu BS Clinical Application of Thromboelastography in Patients With Severe Fever With Thrombocytopenia Syndrome Clinical and Applied Thrombosis/Hemostasis |
| title | Clinical Application of Thromboelastography
in Patients With Severe Fever With Thrombocytopenia Syndrome |
| title_full | Clinical Application of Thromboelastography
in Patients With Severe Fever With Thrombocytopenia Syndrome |
| title_fullStr | Clinical Application of Thromboelastography
in Patients With Severe Fever With Thrombocytopenia Syndrome |
| title_full_unstemmed | Clinical Application of Thromboelastography
in Patients With Severe Fever With Thrombocytopenia Syndrome |
| title_short | Clinical Application of Thromboelastography
in Patients With Severe Fever With Thrombocytopenia Syndrome |
| title_sort | clinical application of thromboelastography in patients with severe fever with thrombocytopenia syndrome |
| url | https://doi.org/10.1177/10760296231180170 |
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