Oncolytic HSV: Underpinnings of Tumor Susceptibility

Oncolytic HSV: Underpinnings of Tumor Susceptibility

Oncolytic herpes simplex virus (oHSV) is a therapeutic modality that has seen substantial success for the treatment of cancer, though much remains to be improved. Commonly attenuated through the deletion or alteration of the γ<sub>1</sub>34.5 neurovirulence gene, the basis for the succes...

Full description

Bibliographic Details
Main Authors: Chase Kangas, Eric Krawczyk, Bin He
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
herpes simplex virus
oncolytic virus
virotherapy
interferon
STING
T-VEC
Online Access:https://www.mdpi.com/1999-4915/13/7/1408

Similar Items

Similar Items