MAVS mediates a protective immune response in the brain to Rift Valley fever virus.

MAVS mediates a protective immune response in the brain to Rift Valley fever virus.

Rift Valley fever virus (RVFV) is a highly pathogenic mosquito-borne virus capable of causing hepatitis, encephalitis, blindness, hemorrhagic syndrome, and death in humans and livestock. Upon aerosol infection with RVFV, the brain is a major site of viral replication and tissue damage, yet pathogene...

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Bibliographic Details
Main Authors: Nicholas R Hum, Feliza A Bourguet, Aimy Sebastian, Doris Lam, Ashlee M Phillips, Kristina R Sanchez, Amy Rasley, Gabriela G Loots, Dina R Weilhammer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010231

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