Polymers in the Medical Antiviral Front-Line
Antiviral polymers are part of a major campaign led by the scientific community in recent years. Facing this most demanding of campaigns, two main approaches have been undertaken by scientists. First, the classic approach involves the development of relatively small molecules having antiviral proper...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-07-01
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| Series: | Polymers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4360/12/8/1727 |
| _version_ | 1797560623893053440 |
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| author | Natanel Jarach Hanna Dodiuk Samuel Kenig |
| author_facet | Natanel Jarach Hanna Dodiuk Samuel Kenig |
| author_sort | Natanel Jarach |
| collection | DOAJ |
| description | Antiviral polymers are part of a major campaign led by the scientific community in recent years. Facing this most demanding of campaigns, two main approaches have been undertaken by scientists. First, the classic approach involves the development of relatively small molecules having antiviral properties to serve as drugs. The other approach involves searching for polymers with antiviral properties to be used as prescription medications or viral spread prevention measures. This second approach took two distinct directions. The first, using polymers as antiviral drug-delivery systems, taking advantage of their biodegradable properties. The second, using polymers with antiviral properties for on-contact virus elimination, which will be the focus of this review. Anti-viral polymers are obtained by either the addition of small antiviral molecules (such as metal ions) to obtain ion-containing polymers with antiviral properties or the use of polymers composed of an organic backbone and electrically charged moieties like polyanions, such as carboxylate containing polymers, or polycations such as quaternary ammonium containing polymers. Other approaches include moieties hybridized by sulphates, carboxylic acids, or amines and/or combining repeating units with a similar chemical structure to common antiviral drugs. Furthermore, elevated temperatures appear to increase the anti-viral effect of ions and other functional moieties. |
| first_indexed | 2024-03-10T18:03:12Z |
| format | Article |
| id | doaj.art-81d0c65b8a944c188abc1d29c648e326 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-10T18:03:12Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-81d0c65b8a944c188abc1d29c648e3262023-11-20T08:43:11ZengMDPI AGPolymers2073-43602020-07-01128172710.3390/polym12081727Polymers in the Medical Antiviral Front-LineNatanel Jarach0Hanna Dodiuk1Samuel Kenig2The Department of Polymer Materials Engineering, Pernick Faculty of Engineering, Shenkar College of Engineering and Design, Raman-Gan 52562, IsraelThe Department of Polymer Materials Engineering, Pernick Faculty of Engineering, Shenkar College of Engineering and Design, Raman-Gan 52562, IsraelThe Department of Polymer Materials Engineering, Pernick Faculty of Engineering, Shenkar College of Engineering and Design, Raman-Gan 52562, IsraelAntiviral polymers are part of a major campaign led by the scientific community in recent years. Facing this most demanding of campaigns, two main approaches have been undertaken by scientists. First, the classic approach involves the development of relatively small molecules having antiviral properties to serve as drugs. The other approach involves searching for polymers with antiviral properties to be used as prescription medications or viral spread prevention measures. This second approach took two distinct directions. The first, using polymers as antiviral drug-delivery systems, taking advantage of their biodegradable properties. The second, using polymers with antiviral properties for on-contact virus elimination, which will be the focus of this review. Anti-viral polymers are obtained by either the addition of small antiviral molecules (such as metal ions) to obtain ion-containing polymers with antiviral properties or the use of polymers composed of an organic backbone and electrically charged moieties like polyanions, such as carboxylate containing polymers, or polycations such as quaternary ammonium containing polymers. Other approaches include moieties hybridized by sulphates, carboxylic acids, or amines and/or combining repeating units with a similar chemical structure to common antiviral drugs. Furthermore, elevated temperatures appear to increase the anti-viral effect of ions and other functional moieties.https://www.mdpi.com/2073-4360/12/8/1727antiviral polymersdrug-delivery polymersantiviral coatingmetal-containing polymersionomers |
| spellingShingle | Natanel Jarach Hanna Dodiuk Samuel Kenig Polymers in the Medical Antiviral Front-Line Polymers antiviral polymers drug-delivery polymers antiviral coating metal-containing polymers ionomers |
| title | Polymers in the Medical Antiviral Front-Line |
| title_full | Polymers in the Medical Antiviral Front-Line |
| title_fullStr | Polymers in the Medical Antiviral Front-Line |
| title_full_unstemmed | Polymers in the Medical Antiviral Front-Line |
| title_short | Polymers in the Medical Antiviral Front-Line |
| title_sort | polymers in the medical antiviral front line |
| topic | antiviral polymers drug-delivery polymers antiviral coating metal-containing polymers ionomers |
| url | https://www.mdpi.com/2073-4360/12/8/1727 |
| work_keys_str_mv | AT nataneljarach polymersinthemedicalantiviralfrontline AT hannadodiuk polymersinthemedicalantiviralfrontline AT samuelkenig polymersinthemedicalantiviralfrontline |