The contemporaneous epidemic of chronic, copper deficiency
The classical deficiency diseases have nearly disappeared from the industrialised world and are thought to be found largely in sub-Saharan Africa and South Asia. More than 80 collected medical articles, mostly from Europe and North America, describe more than 9000 people with low concentrations of c...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2022-01-01
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| Series: | Journal of Nutritional Science |
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| Online Access: | https://www.cambridge.org/core/product/identifier/S2048679022000830/type/journal_article |
| _version_ | 1811156000000966656 |
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| author | Leslie M. Klevay |
| author_facet | Leslie M. Klevay |
| author_sort | Leslie M. Klevay |
| collection | DOAJ |
| description | The classical deficiency diseases have nearly disappeared from the industrialised world and are thought to be found largely in sub-Saharan Africa and South Asia. More than 80 collected medical articles, mostly from Europe and North America, describe more than 9000 people with low concentrations of copper in organs or tissues or impaired metabolic pathways dependent on copper. More than a dozen articles reveal improved anatomy, chemistry or physiology in more than 1000 patients from supplements containing copper. These criteria are diagnostic of deficiency according to The Oxford Textbook of Medicine. Alzheimer's disease, ischaemic heart disease and osteoporosis receive major emphasis here. However, impaired vision, myelodysplastic syndrome and peripheral neuropathy are mentioned. Copper deficiency probably causes some common, contemporaneous diseases. Advice is provided about opportunities for research. Seemingly authoritative statements concerning the rarity of nutritional deficiency in developed countries are wrong. |
| first_indexed | 2024-04-10T04:43:00Z |
| format | Article |
| id | doaj.art-81d0d96d32cb4d4d8e34ad43bed0d604 |
| institution | Directory Open Access Journal |
| issn | 2048-6790 |
| language | English |
| last_indexed | 2024-04-10T04:43:00Z |
| publishDate | 2022-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Nutritional Science |
| spelling | doaj.art-81d0d96d32cb4d4d8e34ad43bed0d6042023-03-09T12:38:45ZengCambridge University PressJournal of Nutritional Science2048-67902022-01-011110.1017/jns.2022.83The contemporaneous epidemic of chronic, copper deficiencyLeslie M. Klevay0https://orcid.org/0000-0002-7636-6987Internal Medicine, University of North Dakota, School of Medicine and Health Sciences, Grand Forks, ND 58202-9037, USAThe classical deficiency diseases have nearly disappeared from the industrialised world and are thought to be found largely in sub-Saharan Africa and South Asia. More than 80 collected medical articles, mostly from Europe and North America, describe more than 9000 people with low concentrations of copper in organs or tissues or impaired metabolic pathways dependent on copper. More than a dozen articles reveal improved anatomy, chemistry or physiology in more than 1000 patients from supplements containing copper. These criteria are diagnostic of deficiency according to The Oxford Textbook of Medicine. Alzheimer's disease, ischaemic heart disease and osteoporosis receive major emphasis here. However, impaired vision, myelodysplastic syndrome and peripheral neuropathy are mentioned. Copper deficiency probably causes some common, contemporaneous diseases. Advice is provided about opportunities for research. Seemingly authoritative statements concerning the rarity of nutritional deficiency in developed countries are wrong.https://www.cambridge.org/core/product/identifier/S2048679022000830/type/journal_articleAlzheimer's diseaseCopper deficiencyIschaemic heart diseaseMyelodysplastic syndromeOsteoporosisPeripheral neuropathy |
| spellingShingle | Leslie M. Klevay The contemporaneous epidemic of chronic, copper deficiency Journal of Nutritional Science Alzheimer's disease Copper deficiency Ischaemic heart disease Myelodysplastic syndrome Osteoporosis Peripheral neuropathy |
| title | The contemporaneous epidemic of chronic, copper deficiency |
| title_full | The contemporaneous epidemic of chronic, copper deficiency |
| title_fullStr | The contemporaneous epidemic of chronic, copper deficiency |
| title_full_unstemmed | The contemporaneous epidemic of chronic, copper deficiency |
| title_short | The contemporaneous epidemic of chronic, copper deficiency |
| title_sort | contemporaneous epidemic of chronic copper deficiency |
| topic | Alzheimer's disease Copper deficiency Ischaemic heart disease Myelodysplastic syndrome Osteoporosis Peripheral neuropathy |
| url | https://www.cambridge.org/core/product/identifier/S2048679022000830/type/journal_article |
| work_keys_str_mv | AT lesliemklevay thecontemporaneousepidemicofchroniccopperdeficiency AT lesliemklevay contemporaneousepidemicofchroniccopperdeficiency |