Interferon gamma effect on immune mediator production in human nerve cells infected by two strains of Toxoplasma gondii

Interferon gamma effect on immune mediator production in human nerve cells infected by two strains of Toxoplasma gondii

Interferon gamma (IFN-γ) is the major immune mediator that prevents toxoplasmic encephalitis in murine models. The lack of IFN-γ secretion causes reactivation of latent T. gondii infection that may confer a risk for severe toxoplasmic encephalitis. We analyse the effect of IFN-γ on immune mediator p...

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Bibliographic Details
Main Authors: Mammari Nour, Vignoles Philippe, Halabi Mohamad Adnan, Dardé Marie-Laure, Courtioux Bertrand
Format: Article
Language:English
Published: EDP Sciences 2015-01-01
Series:Parasite
Subjects:
Toxoplasma gondii
Human nerve cells
IFN-γ
Immunity
Online Access:http://dx.doi.org/10.1051/parasite/2015039

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