Cellular Uptake and Phototoxicity Optimization of Arene Ruthenium Porphyrin Derivatives

Cellular Uptake and Phototoxicity Optimization of Arene Ruthenium Porphyrin Derivatives

In this study, dinuclear and tetranuclear arene ruthenium porphyrins were synthesized and assessed for their potential as photosensitizers (PSs) in photodynamic therapy (PDT) using the Colo205 colon cancer cell line as a model system. Reactive oxygen species (ROS) production, cellular uptake, impact...

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Bibliographic Details
Main Authors: Zeinab Janbeih, Manuel Gallardo-Villagrán, Bruno Therrien, Mona Diab-Assaf, Bertrand Liagre, Ludmil Benov
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Inorganics
Subjects:
photodynamic therapy
arene ruthenium complexes
porphyrin
colon cancer
photosensitizers
Online Access:https://www.mdpi.com/2304-6740/12/3/86

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