A case of extended spectrum beta-lactamase producing Salmonella enterica serotype paratyphi A from India
Enteric fever caused by Salmonella enterica is a systemic infection with high rates of morbidity and mortality. Increasing antibiotic resistance in S. enterica has led to shift in the choice of antibiotics used against this organism from chloramphenicol and ampicillin to trimethoprim-sulfamethoxazol...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2015;volume=58;issue=1;spage=113;epage=114;aulast=Roy |
| _version_ | 1818543953576722432 |
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| author | Priyamvada Roy Deepti Rawat Sonia Malik |
| author_facet | Priyamvada Roy Deepti Rawat Sonia Malik |
| author_sort | Priyamvada Roy |
| collection | DOAJ |
| description | Enteric fever caused by Salmonella enterica is a systemic infection with high rates of morbidity and mortality. Increasing antibiotic resistance in S. enterica has led to shift in the choice of antibiotics used against this organism from chloramphenicol and ampicillin to trimethoprim-sulfamethoxazole, fluoroquinolones, and extended-spectrum cephalosporins. Resistance to cephalosporins, due to the production of extended-spectrum beta-lactamases (ESBLs), is the cause of serious concern worldwide. So far, these enzymes have been detected in many species of the family Enterobacteriaceae including different serotypes of S. enterica. To the best of our knowledge, however, ESBL production in Salmonella Paratyphi A has not yet been reported from India. We present here a case of ESBL producing Salmonella Paratyphi A from India. This is a worrisome finding with grave clinical implications, since the dissemination of this resistance trait would further limit the therapeutic options available for the treatment of enteric fever. |
| first_indexed | 2024-12-11T22:42:08Z |
| format | Article |
| id | doaj.art-81e207d7404242d7b85d13dd0370e6ef |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-12-11T22:42:08Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-81e207d7404242d7b85d13dd0370e6ef2022-12-22T00:47:45ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292015-01-0158111311410.4103/0377-4929.151205A case of extended spectrum beta-lactamase producing Salmonella enterica serotype paratyphi A from IndiaPriyamvada RoyDeepti RawatSonia MalikEnteric fever caused by Salmonella enterica is a systemic infection with high rates of morbidity and mortality. Increasing antibiotic resistance in S. enterica has led to shift in the choice of antibiotics used against this organism from chloramphenicol and ampicillin to trimethoprim-sulfamethoxazole, fluoroquinolones, and extended-spectrum cephalosporins. Resistance to cephalosporins, due to the production of extended-spectrum beta-lactamases (ESBLs), is the cause of serious concern worldwide. So far, these enzymes have been detected in many species of the family Enterobacteriaceae including different serotypes of S. enterica. To the best of our knowledge, however, ESBL production in Salmonella Paratyphi A has not yet been reported from India. We present here a case of ESBL producing Salmonella Paratyphi A from India. This is a worrisome finding with grave clinical implications, since the dissemination of this resistance trait would further limit the therapeutic options available for the treatment of enteric fever.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2015;volume=58;issue=1;spage=113;epage=114;aulast=RoyExtended spectrum beta-lactamaseIndiaSalmonella enterica subspecies enterica serotype paratyphi A |
| spellingShingle | Priyamvada Roy Deepti Rawat Sonia Malik A case of extended spectrum beta-lactamase producing Salmonella enterica serotype paratyphi A from India Indian Journal of Pathology and Microbiology Extended spectrum beta-lactamase India Salmonella enterica subspecies enterica serotype paratyphi A |
| title | A case of extended spectrum beta-lactamase producing Salmonella enterica serotype paratyphi A from India |
| title_full | A case of extended spectrum beta-lactamase producing Salmonella enterica serotype paratyphi A from India |
| title_fullStr | A case of extended spectrum beta-lactamase producing Salmonella enterica serotype paratyphi A from India |
| title_full_unstemmed | A case of extended spectrum beta-lactamase producing Salmonella enterica serotype paratyphi A from India |
| title_short | A case of extended spectrum beta-lactamase producing Salmonella enterica serotype paratyphi A from India |
| title_sort | case of extended spectrum beta lactamase producing salmonella enterica serotype paratyphi a from india |
| topic | Extended spectrum beta-lactamase India Salmonella enterica subspecies enterica serotype paratyphi A |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2015;volume=58;issue=1;spage=113;epage=114;aulast=Roy |
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