Cardiometabolic Effects of Postnatal High-Fat Diet Consumption in Offspring Exposed to Maternal Protein Restriction In Utero
In recent decades, the high incidence of infectious and parasitic diseases has been replaced by a high prevalence of chronic and degenerative diseases. Concomitantly, there have been profound changes in the behavior and eating habits of families around the world, characterizing a “nutritional transi...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-05-01
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| Series: | Frontiers in Physiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2022.829920/full |
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| author | Aiany Cibelle Simões-Alves Ana Paula Fonseca Cabral Arcoverde-Mello Jéssica de Oliveira Campos Almir Gonçalves Wanderley Carol Virginia Gois Leandro João Henrique da Costa-Silva Viviane de Oliveira Nogueira Souza |
| author_facet | Aiany Cibelle Simões-Alves Ana Paula Fonseca Cabral Arcoverde-Mello Jéssica de Oliveira Campos Almir Gonçalves Wanderley Carol Virginia Gois Leandro João Henrique da Costa-Silva Viviane de Oliveira Nogueira Souza |
| author_sort | Aiany Cibelle Simões-Alves |
| collection | DOAJ |
| description | In recent decades, the high incidence of infectious and parasitic diseases has been replaced by a high prevalence of chronic and degenerative diseases. Concomitantly, there have been profound changes in the behavior and eating habits of families around the world, characterizing a “nutritional transition” phenomenon, which refers to a shift in diet in response to modernization, urbanization, or economic development from undernutrition to the excessive consumption of hypercaloric and ultra-processed foods. Protein malnutrition that was a health problem in the first half of the 20th century has now been replaced by high-fat diets, especially diets high in saturated fat, predisposing consumers to overweight and obesity. This panorama points us to the alarming coexistence of both malnutrition and obesity in the same population. In this way, individuals whose mothers were undernourished early in pregnancy and then exposed to postnatal hyperlipidic nutrition have increased risk factors for developing metabolic dysfunction and cardiovascular diseases in adulthood. Thus, our major aim was to review the cardiometabolic effects resulting from postnatal hyperlipidic diets in protein-restricted subjects, as well as to examine the epigenetic repercussions occasioned by the nutritional transition. |
| first_indexed | 2024-04-14T00:04:05Z |
| format | Article |
| id | doaj.art-81e3e9a1ebd64f089ea7530a4f56c346 |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-04-14T00:04:05Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-81e3e9a1ebd64f089ea7530a4f56c3462022-12-22T02:23:36ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2022-05-011310.3389/fphys.2022.829920829920Cardiometabolic Effects of Postnatal High-Fat Diet Consumption in Offspring Exposed to Maternal Protein Restriction In UteroAiany Cibelle Simões-Alves0Ana Paula Fonseca Cabral Arcoverde-Mello1Jéssica de Oliveira Campos2Almir Gonçalves Wanderley3Carol Virginia Gois Leandro4João Henrique da Costa-Silva5Viviane de Oliveira Nogueira Souza6Laboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Department of Physical Education and Sport Sciences, Universidade Federal de Pernambuco UFPE, Vitória de Santo Antão, BrazilLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Department of Physical Education and Sport Sciences, Universidade Federal de Pernambuco UFPE, Vitória de Santo Antão, BrazilLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Department of Physical Education and Sport Sciences, Universidade Federal de Pernambuco UFPE, Vitória de Santo Antão, BrazilDepartment of Physiology and Pharmacology, Universidade Federal de Pernambuco UFPE, Recife, BrazilLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Department of Physical Education and Sport Sciences, Universidade Federal de Pernambuco UFPE, Vitória de Santo Antão, BrazilLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Department of Physical Education and Sport Sciences, Universidade Federal de Pernambuco UFPE, Vitória de Santo Antão, BrazilLaboratory of Nutrition, Physical Activity and Phenotypic Plasticity, Department of Physical Education and Sport Sciences, Universidade Federal de Pernambuco UFPE, Vitória de Santo Antão, BrazilIn recent decades, the high incidence of infectious and parasitic diseases has been replaced by a high prevalence of chronic and degenerative diseases. Concomitantly, there have been profound changes in the behavior and eating habits of families around the world, characterizing a “nutritional transition” phenomenon, which refers to a shift in diet in response to modernization, urbanization, or economic development from undernutrition to the excessive consumption of hypercaloric and ultra-processed foods. Protein malnutrition that was a health problem in the first half of the 20th century has now been replaced by high-fat diets, especially diets high in saturated fat, predisposing consumers to overweight and obesity. This panorama points us to the alarming coexistence of both malnutrition and obesity in the same population. In this way, individuals whose mothers were undernourished early in pregnancy and then exposed to postnatal hyperlipidic nutrition have increased risk factors for developing metabolic dysfunction and cardiovascular diseases in adulthood. Thus, our major aim was to review the cardiometabolic effects resulting from postnatal hyperlipidic diets in protein-restricted subjects, as well as to examine the epigenetic repercussions occasioned by the nutritional transition.https://www.frontiersin.org/articles/10.3389/fphys.2022.829920/fullhypertensionobesitynutrition transitionsaturated fatty acidsdyslipidemia |
| spellingShingle | Aiany Cibelle Simões-Alves Ana Paula Fonseca Cabral Arcoverde-Mello Jéssica de Oliveira Campos Almir Gonçalves Wanderley Carol Virginia Gois Leandro João Henrique da Costa-Silva Viviane de Oliveira Nogueira Souza Cardiometabolic Effects of Postnatal High-Fat Diet Consumption in Offspring Exposed to Maternal Protein Restriction In Utero Frontiers in Physiology hypertension obesity nutrition transition saturated fatty acids dyslipidemia |
| title | Cardiometabolic Effects of Postnatal High-Fat Diet Consumption in Offspring Exposed to Maternal Protein Restriction In Utero |
| title_full | Cardiometabolic Effects of Postnatal High-Fat Diet Consumption in Offspring Exposed to Maternal Protein Restriction In Utero |
| title_fullStr | Cardiometabolic Effects of Postnatal High-Fat Diet Consumption in Offspring Exposed to Maternal Protein Restriction In Utero |
| title_full_unstemmed | Cardiometabolic Effects of Postnatal High-Fat Diet Consumption in Offspring Exposed to Maternal Protein Restriction In Utero |
| title_short | Cardiometabolic Effects of Postnatal High-Fat Diet Consumption in Offspring Exposed to Maternal Protein Restriction In Utero |
| title_sort | cardiometabolic effects of postnatal high fat diet consumption in offspring exposed to maternal protein restriction in utero |
| topic | hypertension obesity nutrition transition saturated fatty acids dyslipidemia |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2022.829920/full |
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