OSMOLYTIC AND ADSORPTIVE ACTIVITIES DETERMINATION IN VITRO OF OINTMENT COMPONENTS ON THE BASIS OF CO2 EXTRACT FROM SEEDS OF SCHIZANDRA CHINENSIS
There are data about positive effects from treatment of different skin diseases, sluggishly granulating wounds, and trophic ulcers with drugs based on Schizandra chinensis in literature sources. The purpose of this work is elaboration of soft external drug form – ointment on the basis of CO2 extract...
| প্রধান লেখক: | , |
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| বিন্যাস: | প্রবন্ধ |
| ভাষা: | Russian |
| প্রকাশিত: |
Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute
2015-09-01
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| মালা: | Фармация и фармакология (Пятигорск) |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://www.pharmpharm.ru/jour/article/view/65 |
| _version_ | 1826559416190631936 |
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| author | M. S. Makieva Yu. A. Morozov |
| author_facet | M. S. Makieva Yu. A. Morozov |
| author_sort | M. S. Makieva |
| collection | DOAJ |
| description | There are data about positive effects from treatment of different skin diseases, sluggishly granulating wounds, and trophic ulcers with drugs based on Schizandra chinensis in literature sources. The purpose of this work is elaboration of soft external drug form – ointment on the basis of CO2 extract of Schizandra chinensis seeds. Biopharmaceutical researches in vitro were carried out to choose optimal ointment composition with osmolytic and absorptive activity. Researches on osmolytic activity determination were conducted by the common method of equilibrium dialysis through semi-permeable membrane; adsorption activity of model ointment compositions was registered on their capability to sorb coloring agent. Thus we have established that all model ointment compositions under consideration have osmolytic (by the efficiency as well as by duration) and adsorptive activity and can be used at different stages of wound process |
| first_indexed | 2024-04-10T01:37:01Z |
| format | Article |
| id | doaj.art-81e592542a0e4636be532b2928e5ddbe |
| institution | Directory Open Access Journal |
| issn | 2307-9266 2413-2241 |
| language | Russian |
| last_indexed | 2025-03-14T09:00:02Z |
| publishDate | 2015-09-01 |
| publisher | Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute |
| record_format | Article |
| series | Фармация и фармакология (Пятигорск) |
| spelling | doaj.art-81e592542a0e4636be532b2928e5ddbe2025-03-02T12:43:12ZrusVolgograd State Medical University, Pyatigorsk Medical and Pharmaceutical InstituteФармация и фармакология (Пятигорск)2307-92662413-22412015-09-0126(7)424710.19163/2307-9266-2014-2-6(7)-42-4765OSMOLYTIC AND ADSORPTIVE ACTIVITIES DETERMINATION IN VITRO OF OINTMENT COMPONENTS ON THE BASIS OF CO2 EXTRACT FROM SEEDS OF SCHIZANDRA CHINENSISM. S. Makieva0Yu. A. Morozov1North Ossetian State Univerity after K.L. Khetagurov, VladikavkazNorth Ossetian State Univerity after K.L. Khetagurov, VladikavkazThere are data about positive effects from treatment of different skin diseases, sluggishly granulating wounds, and trophic ulcers with drugs based on Schizandra chinensis in literature sources. The purpose of this work is elaboration of soft external drug form – ointment on the basis of CO2 extract of Schizandra chinensis seeds. Biopharmaceutical researches in vitro were carried out to choose optimal ointment composition with osmolytic and absorptive activity. Researches on osmolytic activity determination were conducted by the common method of equilibrium dialysis through semi-permeable membrane; adsorption activity of model ointment compositions was registered on their capability to sorb coloring agent. Thus we have established that all model ointment compositions under consideration have osmolytic (by the efficiency as well as by duration) and adsorptive activity and can be used at different stages of wound processhttps://www.pharmpharm.ru/jour/article/view/65schizandra chinensisointmentsointment basesbiopharmacyosmolytic activityadsorptive activity |
| spellingShingle | M. S. Makieva Yu. A. Morozov OSMOLYTIC AND ADSORPTIVE ACTIVITIES DETERMINATION IN VITRO OF OINTMENT COMPONENTS ON THE BASIS OF CO2 EXTRACT FROM SEEDS OF SCHIZANDRA CHINENSIS Фармация и фармакология (Пятигорск) schizandra chinensis ointments ointment bases biopharmacy osmolytic activity adsorptive activity |
| title | OSMOLYTIC AND ADSORPTIVE ACTIVITIES DETERMINATION IN VITRO OF OINTMENT COMPONENTS ON THE BASIS OF CO2 EXTRACT FROM SEEDS OF SCHIZANDRA CHINENSIS |
| title_full | OSMOLYTIC AND ADSORPTIVE ACTIVITIES DETERMINATION IN VITRO OF OINTMENT COMPONENTS ON THE BASIS OF CO2 EXTRACT FROM SEEDS OF SCHIZANDRA CHINENSIS |
| title_fullStr | OSMOLYTIC AND ADSORPTIVE ACTIVITIES DETERMINATION IN VITRO OF OINTMENT COMPONENTS ON THE BASIS OF CO2 EXTRACT FROM SEEDS OF SCHIZANDRA CHINENSIS |
| title_full_unstemmed | OSMOLYTIC AND ADSORPTIVE ACTIVITIES DETERMINATION IN VITRO OF OINTMENT COMPONENTS ON THE BASIS OF CO2 EXTRACT FROM SEEDS OF SCHIZANDRA CHINENSIS |
| title_short | OSMOLYTIC AND ADSORPTIVE ACTIVITIES DETERMINATION IN VITRO OF OINTMENT COMPONENTS ON THE BASIS OF CO2 EXTRACT FROM SEEDS OF SCHIZANDRA CHINENSIS |
| title_sort | osmolytic and adsorptive activities determination in vitro of ointment components on the basis of co2 extract from seeds of schizandra chinensis |
| topic | schizandra chinensis ointments ointment bases biopharmacy osmolytic activity adsorptive activity |
| url | https://www.pharmpharm.ru/jour/article/view/65 |
| work_keys_str_mv | AT msmakieva osmolyticandadsorptiveactivitiesdeterminationinvitroofointmentcomponentsonthebasisofco2extractfromseedsofschizandrachinensis AT yuamorozov osmolyticandadsorptiveactivitiesdeterminationinvitroofointmentcomponentsonthebasisofco2extractfromseedsofschizandrachinensis |