Electrochemiluminescence Systems for the Detection of Biomarkers: Strategical and Technological Advances
Electrochemiluminescence (ECL)-based sensing systems rely on light emissions from luminophores, which are generated by high-energy electron transfer reactions between electrogenerated species on an electrode. ECL systems have been widely used in the detection and monitoring of diverse, disease-relat...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/12/9/738 |
| _version_ | 1827662909039181824 |
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| author | Seung-Min Yoo Yong-Min Jeon Seo-Young Heo |
| author_facet | Seung-Min Yoo Yong-Min Jeon Seo-Young Heo |
| author_sort | Seung-Min Yoo |
| collection | DOAJ |
| description | Electrochemiluminescence (ECL)-based sensing systems rely on light emissions from luminophores, which are generated by high-energy electron transfer reactions between electrogenerated species on an electrode. ECL systems have been widely used in the detection and monitoring of diverse, disease-related biomarkers due to their high selectivity and fast response times, as well as their spatial and temporal control of luminance, high controllability, and a wide detection range. This review focuses on the recent strategic and technological advances in ECL-based biomarker detection systems. We introduce several sensing systems for medical applications that are classified according to the reactions that drive ECL signal emissions. We also provide recent examples of sensing strategies and technologies based on factors that enhance sensitivity and multiplexing abilities as well as simplify sensing procedures. This review also discusses the potential strategies and technologies for the development of ECL systems with an enhanced detection ability. |
| first_indexed | 2024-03-10T00:35:29Z |
| format | Article |
| id | doaj.art-81ea99f634f041a8815c33e7f69f25f8 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-10T00:35:29Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-81ea99f634f041a8815c33e7f69f25f82023-11-23T15:18:20ZengMDPI AGBiosensors2079-63742022-09-0112973810.3390/bios12090738Electrochemiluminescence Systems for the Detection of Biomarkers: Strategical and Technological AdvancesSeung-Min Yoo0Yong-Min Jeon1Seo-Young Heo2School of Integrative Engineering, Chung-Ang University, Seoul 06974, KoreaSchool of Integrative Engineering, Chung-Ang University, Seoul 06974, KoreaSchool of Integrative Engineering, Chung-Ang University, Seoul 06974, KoreaElectrochemiluminescence (ECL)-based sensing systems rely on light emissions from luminophores, which are generated by high-energy electron transfer reactions between electrogenerated species on an electrode. ECL systems have been widely used in the detection and monitoring of diverse, disease-related biomarkers due to their high selectivity and fast response times, as well as their spatial and temporal control of luminance, high controllability, and a wide detection range. This review focuses on the recent strategic and technological advances in ECL-based biomarker detection systems. We introduce several sensing systems for medical applications that are classified according to the reactions that drive ECL signal emissions. We also provide recent examples of sensing strategies and technologies based on factors that enhance sensitivity and multiplexing abilities as well as simplify sensing procedures. This review also discusses the potential strategies and technologies for the development of ECL systems with an enhanced detection ability.https://www.mdpi.com/2079-6374/12/9/738electrochemiluminescencebiomarkerdetectionluminophoreco-reactantresonance energy transfer |
| spellingShingle | Seung-Min Yoo Yong-Min Jeon Seo-Young Heo Electrochemiluminescence Systems for the Detection of Biomarkers: Strategical and Technological Advances Biosensors electrochemiluminescence biomarker detection luminophore co-reactant resonance energy transfer |
| title | Electrochemiluminescence Systems for the Detection of Biomarkers: Strategical and Technological Advances |
| title_full | Electrochemiluminescence Systems for the Detection of Biomarkers: Strategical and Technological Advances |
| title_fullStr | Electrochemiluminescence Systems for the Detection of Biomarkers: Strategical and Technological Advances |
| title_full_unstemmed | Electrochemiluminescence Systems for the Detection of Biomarkers: Strategical and Technological Advances |
| title_short | Electrochemiluminescence Systems for the Detection of Biomarkers: Strategical and Technological Advances |
| title_sort | electrochemiluminescence systems for the detection of biomarkers strategical and technological advances |
| topic | electrochemiluminescence biomarker detection luminophore co-reactant resonance energy transfer |
| url | https://www.mdpi.com/2079-6374/12/9/738 |
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