Subthalamic nucleus deep brain stimulation alleviates oxidative stress via mitophagy in Parkinson’s disease

Subthalamic nucleus deep brain stimulation alleviates oxidative stress via mitophagy in Parkinson’s disease

Abstract Subthalamic nucleus deep brain stimulation (STN-DBS) has the potential to delay Parkinson’s disease (PD) progression. Whether oxidative stress participates in the neuroprotective effects of DBS and related signaling pathways remains unknown. To address this, we applied STN-DBS to mice and m...

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Bibliographic Details
Main Authors: Yingchuan Chen, Guanyu Zhu, Tianshuo Yuan, Ruoyu Ma, Xin Zhang, Fangang Meng, Anchao Yang, Tingting Du, Jianguo Zhang
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-024-00668-4

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