Diabetic Retinopathy. Morphofunctional State of the Retina in Pancreas Recipients

Diabetes mellitus (DM) is one of the most common and rapidly progressing diseases worldwide. Diabetic retinopathy (DR) is a common complication of diabetes and the main cause of vision loss in middle-aged and elderly people. The development and progression of DR is closely related to the duration of...

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Main Authors: I. V. Vorobyeva, L. K. Moshetova, A. V. Pinchuk, E. V. Bulava, K. E. Lazareva, N. S. Zhuravel
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2021-10-01
Series:Oftalʹmologiâ
Subjects:
Online Access:https://www.ophthalmojournal.com/opht/article/view/1601
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author I. V. Vorobyeva
L. K. Moshetova
A. V. Pinchuk
E. V. Bulava
K. E. Lazareva
N. S. Zhuravel
author_facet I. V. Vorobyeva
L. K. Moshetova
A. V. Pinchuk
E. V. Bulava
K. E. Lazareva
N. S. Zhuravel
author_sort I. V. Vorobyeva
collection DOAJ
description Diabetes mellitus (DM) is one of the most common and rapidly progressing diseases worldwide. Diabetic retinopathy (DR) is a common complication of diabetes and the main cause of vision loss in middle-aged and elderly people. The development and progression of DR is closely related to the duration of diabetes, hyperglycemia, and arterial hypertension. There is growing evidence that inflammation is one of the key links in the pathogenesis of diabetic retinal damage, but the exact molecular mechanisms remain to be known. Pancreas transplantation (PT) is currently the only effective treatment for diabetes that restores normal physiological glucose metabolism. Due to the limited number of PT surgeries associated with the severity of intra- and postoperative complications and the acute issue of organ donation, studies on the assessment of DR after PT are few and contradictory. There is a need for further studies of the DR state after PT with the study of the influence of risk factors, determination of the level of immunological markers and the use of modern instrumental research methods to create effective patient management regimens in the postoperative period.
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spelling doaj.art-81f283cb1cf04660b620fa44e7d458a22024-10-17T16:12:00ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452021-10-0118345946910.18008/1816-5095-2021-3-459-469781Diabetic Retinopathy. Morphofunctional State of the Retina in Pancreas RecipientsI. V. Vorobyeva0L. K. Moshetova1A. V. Pinchuk2E. V. Bulava3K. E. Lazareva4N. S. Zhuravel5Russian Medical Academy of Continuous Professional EducationRussian Medical Academy of Continuous Professional EducationN.V. Sklifosovskiy Research Institute for Emergency Medical Aid; A.I. Evdokimov Moscow University of Medicine & Dentistry; Research Institute of Public Health Organization and Medical ManagementRussian Medical Academy of Continuous Professional EducationN.V. Sklifosovskiy Research Institute for Emergency Medical Aid; A.I. Evdokimov Moscow University of Medicine & DentistryN.V. Sklifosovskiy Research Institute for Emergency Medical AidDiabetes mellitus (DM) is one of the most common and rapidly progressing diseases worldwide. Diabetic retinopathy (DR) is a common complication of diabetes and the main cause of vision loss in middle-aged and elderly people. The development and progression of DR is closely related to the duration of diabetes, hyperglycemia, and arterial hypertension. There is growing evidence that inflammation is one of the key links in the pathogenesis of diabetic retinal damage, but the exact molecular mechanisms remain to be known. Pancreas transplantation (PT) is currently the only effective treatment for diabetes that restores normal physiological glucose metabolism. Due to the limited number of PT surgeries associated with the severity of intra- and postoperative complications and the acute issue of organ donation, studies on the assessment of DR after PT are few and contradictory. There is a need for further studies of the DR state after PT with the study of the influence of risk factors, determination of the level of immunological markers and the use of modern instrumental research methods to create effective patient management regimens in the postoperative period.https://www.ophthalmojournal.com/opht/article/view/1601diabetes mellituspancreas transplantationdiabetic retinopathydiabetic macular edemapathogenesisclassificationoptical coherence tomography angiography
spellingShingle I. V. Vorobyeva
L. K. Moshetova
A. V. Pinchuk
E. V. Bulava
K. E. Lazareva
N. S. Zhuravel
Diabetic Retinopathy. Morphofunctional State of the Retina in Pancreas Recipients
Oftalʹmologiâ
diabetes mellitus
pancreas transplantation
diabetic retinopathy
diabetic macular edema
pathogenesis
classification
optical coherence tomography angiography
title Diabetic Retinopathy. Morphofunctional State of the Retina in Pancreas Recipients
title_full Diabetic Retinopathy. Morphofunctional State of the Retina in Pancreas Recipients
title_fullStr Diabetic Retinopathy. Morphofunctional State of the Retina in Pancreas Recipients
title_full_unstemmed Diabetic Retinopathy. Morphofunctional State of the Retina in Pancreas Recipients
title_short Diabetic Retinopathy. Morphofunctional State of the Retina in Pancreas Recipients
title_sort diabetic retinopathy morphofunctional state of the retina in pancreas recipients
topic diabetes mellitus
pancreas transplantation
diabetic retinopathy
diabetic macular edema
pathogenesis
classification
optical coherence tomography angiography
url https://www.ophthalmojournal.com/opht/article/view/1601
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AT evbulava diabeticretinopathymorphofunctionalstateoftheretinainpancreasrecipients
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