Funding sources and breast cancer research frame.

This study aims to analyze the formation of the frame of breast cancer research. To test our hypothesis that the research frame depends on the funding sources, we collected the abstracts of 48,448 breast cancer research papers from PubMed and applied structural topic modeling, word network analysis,...

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Main Author: Wonkwang Jo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0238026
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author Wonkwang Jo
author_facet Wonkwang Jo
author_sort Wonkwang Jo
collection DOAJ
description This study aims to analyze the formation of the frame of breast cancer research. To test our hypothesis that the research frame depends on the funding sources, we collected the abstracts of 48,448 breast cancer research papers from PubMed and applied structural topic modeling, word network analysis, and LASSO logistic regression to the data. In particular, we analyzed the relationship between funding sources and the molecularization of breast cancer knowledge. The results show that government-funded research is likely to have molecular objects or population as the unit of interest, whereas the research not funded by the government is likely to have individual patients as the unit of interest in relation to specific treatments. This phenomenon is attributed to the different interests of government institutions and the private sector. This study improves our understanding of molecularization and medical knowledge production.
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spelling doaj.art-81f72922298f4f9d9025727e894751702022-12-21T20:40:04ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-01158e023802610.1371/journal.pone.0238026Funding sources and breast cancer research frame.Wonkwang JoThis study aims to analyze the formation of the frame of breast cancer research. To test our hypothesis that the research frame depends on the funding sources, we collected the abstracts of 48,448 breast cancer research papers from PubMed and applied structural topic modeling, word network analysis, and LASSO logistic regression to the data. In particular, we analyzed the relationship between funding sources and the molecularization of breast cancer knowledge. The results show that government-funded research is likely to have molecular objects or population as the unit of interest, whereas the research not funded by the government is likely to have individual patients as the unit of interest in relation to specific treatments. This phenomenon is attributed to the different interests of government institutions and the private sector. This study improves our understanding of molecularization and medical knowledge production.https://doi.org/10.1371/journal.pone.0238026
spellingShingle Wonkwang Jo
Funding sources and breast cancer research frame.
PLoS ONE
title Funding sources and breast cancer research frame.
title_full Funding sources and breast cancer research frame.
title_fullStr Funding sources and breast cancer research frame.
title_full_unstemmed Funding sources and breast cancer research frame.
title_short Funding sources and breast cancer research frame.
title_sort funding sources and breast cancer research frame
url https://doi.org/10.1371/journal.pone.0238026
work_keys_str_mv AT wonkwangjo fundingsourcesandbreastcancerresearchframe