Identification of a Host-Targeted Compound to Control Typhoid Fever

Identification of a Host-Targeted Compound to Control Typhoid Fever

ABSTRACT Typhoid fever is caused primarily by the enteric microbe Salmonella enterica serovar Typhi and remains a major global health problem with approximately 14 million new infections and 136,000 fatalities annually. While there are antibiotic options available to treat the disease, the global in...

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Bibliographic Details
Main Authors: Ky V. Hoang, Katherine Woolard, Ching Yang, Christian Melander, John S. Gunn
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:Microbiology Spectrum
Subjects:
KH-1-2
host-targeted therapy
typhoid fever
immunomodulation
Salmonella Typhi
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00619-22

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