Propofol Alleviates DNA Damage Induced by Oxygen Glucose Deprivation and Reperfusion via FoxO1 Nuclear Translocation in H9c2 Cells

Propofol Alleviates DNA Damage Induced by Oxygen Glucose Deprivation and Reperfusion via FoxO1 Nuclear Translocation in H9c2 Cells

Ischemia/reperfusion (I/R) injury induces irreversible oxidative stress damage to the cardiac myocytes. Many studies have revealed that propofol alleviates the important organelle-mediated injury from oxidative stress in vitro. However, it remains unclear whether propofol prevents I/R-induced DNA da...

Full description

Bibliographic Details
Main Authors: Dandan Zhou, Jinqiang Zhuang, Yihui Wang, Dandan Zhao, Lidong Zhao, Shun Zhu, Jinjun Pu, Ming Yin, Hongyu Zhang, Zejian Wang, Jiang Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Physiology
Subjects:
propofol
oxygen glucose deprivation and reperfusion
ROS
DNA damage
FoxO1
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00223/full

Similar Items

Similar Items