Mechanism of canagliflozin-induced vasodilation in resistance mesenteric arteries and the regulation of systemic blood pressure

Mechanism of canagliflozin-induced vasodilation in resistance mesenteric arteries and the regulation of systemic blood pressure

Canagliflozin, a sodium glucose co-transporter 2 (SGLT2) inhibitor, is reported to produce beneficial cardiovascular effects including a reduction in arterial contractility, and blood pressure. However, whether canagliflozin could directly relax resistance mesenteric arteries, underlying molecular m...

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Bibliographic Details
Main Authors:	Ahasanul Hasan, Farzana Zerin, Sreelakshmi N. Menon, Md. Ashraful Alam, Raquibul Hasan
Format:	Article
Language:	English
Published:	Elsevier 2022-12-01
Series:	Journal of Pharmacological Sciences
Subjects:	Canagliflozin Mesenteric arteries Voltage-gated K+ channels Vasorelaxation Blood pressure
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861322000718

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