Justicidin B: A Promising Bioactive Lignan

Justicidin B: A Promising Bioactive Lignan

Adverse effects and drug resistance to the current onchopharmacologicals have increased the demand for alternative novel therapeutics. We herein introduce justicidin B, an arylnaphthalen lignan isolated from different plant origins, especially Justicia, Phyllanthus, Haplophyllum and Linum species. T...

Full description

Bibliographic Details
Main Authors:	Shiva Hemmati, Hassan Seradj
Format:	Article
Language:	English
Published:	MDPI AG 2016-06-01
Series:	Molecules
Subjects:	lignan arylnaphthalene justicidin B distribution chemistry biosynthesis biotechnological production biological activity synthesis chromatography
Online Access:	http://www.mdpi.com/1420-3049/21/7/820

Similar Items

Total synthesis of justicidin B, justicidin E, and taiwanin C: A general and flexible approach toward the synthesis of natural arylnaphthalene lactone lignans
by: Kai Wei, et al.
Published: (2022-12-01)

Transition Metal-Mediated Annulation Approaches for Synthesis of Arylnaphthalene Lignan Lactones
by: Sooyoung Park, et al.
Published: (2020-08-01)

Concise Synthesis of (+)-β- and γ-Apopicropodophyllins, and Dehydrodesoxypodophyllotoxin
by: Jian Xiao, et al.
Published: (2018-11-01)

<i>Linum lewisii</i> Adventitious and Hairy-Roots Cultures as Lignan Plant Factories
by: Roméo Arago Dougué Kentsop, et al.
Published: (2022-08-01)

Using connectivity map to identify natural lignan justicidin A as a NF-κB suppressor
by: Shen-Jeu Won, et al.
Published: (2017-07-01)

Identification of an Arylnaphthalene Lignan Derivative as an Inhibitor against Dengue Virus Serotypes 1 to 4 (DENV-1 to -4) Using a Newly Developed DENV-3 Infectious Clone and Replicon
by: Mingyue Hu, et al.
Published: (2023-08-01)

New Insight into Justicidin B Pathway and Production in <i>Linum austriacum</i>
by: Iride Mascheretti, et al.
Published: (2021-03-01)

6′-Hydroxy Justicidin B Triggers a Critical Imbalance in Ca2+ Homeostasis and Mitochondrion-Dependent Cell Death in Human Leukemia K562 Cells
by: Jiaoyang Luo, et al.
Published: (2018-06-01)

Discovery of molecular mechanisms of lignan justicidin A using L1000 gene expression profiles and the Library of Integrated Network-based Cellular Signatures database
by: Shen-Jeu Won, et al.
Published: (2015-06-01)

A Novel Antiplatelet Aggregation Target of Justicidin B Obtained From Rostellularia Procumbens (L.) Nees
by: Yan-Fang Yang, et al.
Published: (2019-06-01)

Lignans of Sesame (<i>Sesamum indicum</i> L.): A Comprehensive Review
by: Mebeaselassie Andargie, et al.
Published: (2021-02-01)

Essences in Metabolic Engineering of Lignan Biosynthesis
by: Honoo Satake, et al.
Published: (2015-05-01)

Advances in the Synthesis of Lignan Natural Products
by: Xianhe Fang, et al.
Published: (2018-12-01)

Biological functions of lignans in plants
by: Ražná Katarína, et al.
Published: (2021-12-01)

Oxidative Transformations of Lignans
by: Patrik A. Runeberg, et al.
Published: (2019-01-01)

Functional Characterization of UDP-Glycosyltransferases Involved in Anti-viral Lignan Glycosides Biosynthesis in Isatis indigotica
by: Yuping Tan, et al.
Published: (2022-06-01)

Editorial: Lignans: Insights Into Their Biosynthesis, Metabolic Engineering, Analytical Methods and Health Benefits
by: Christophe F. Hano, et al.
Published: (2021-01-01)

The wild allotetraploid sesame genome provides novel insights into evolution and lignan biosynthesis
by: Xiao Wang, et al.
Published: (2023-08-01)

New lignans from leaves of macropiper excelsum /
by: 418801 Russell, Graeme B, et al.

Two lignan glycosides from vitis thunbergh /
by: 496090 Yue-Hua He, et al.

Characterization of Peroxidase and Laccase Gene Families and In Silico Identification of Potential Genes Involved in Upstream Steps of Lignan Formation in Sesame
by: Yedomon Ange Bovys Zoclanclounon, et al.
Published: (2022-08-01)

Long-read transcriptome sequencing provides insight into lignan biosynthesis during fruit development in Schisandra chinensis
by: Chang Pyo Hong, et al.
Published: (2022-01-01)

Bioactive Lignans from Flaxseed: Biological Properties and Patented Recovery Technologies
by: Paola Sangiorgio, et al.
Published: (2023-01-01)

Lignans: Quantitative Analysis of the Research Literature
by: Andy Wai Kan Yeung, et al.
Published: (2020-02-01)

Antioxidant lignans sesamin and sesamolin in sesame (Sesamum indicum L.): A comprehensive review and future prospects
by: Senouwa Segla Koffi DOSSOU, et al.
Published: (2023-01-01)

The chemistry of lignans and their distribution in the plant kingdom /
by: 285126 Mawardi Rahmani, et al.

Advances in the roles and mechanisms of lignans against Alzheimer’s disease
by: Na Han, et al.
Published: (2022-10-01)

Analysis of Softwood Lignans by Comprehensive Two-Dimensional Liquid Chromatography
by: Danil I. Falev, et al.
Published: (2023-12-01)

Structure and Cytotoxicity of Novel Lignans and Lignan Glycosides from the Aerial Parts of <i>Larrea tridentata</i>
by: Akihito Yokosuka, et al.
Published: (2021-10-01)

Antimicrobial Activity of Hydroxymatairesinol (HMR) Lignan#
by: Widad M.K. Al-Ani, et al.
Published: (2017-02-01)

Novel Biphenyl enter lignans from the Rhizomes of Curcuma chuanyujin/
by: Huang, Jing, et al.

IiWRKY34 positively regulates yield, lignan biosynthesis and stress tolerance in Isatis indigotica
by: Ying Xiao, et al.
Published: (2020-12-01)

Analytical and Preparative Separation of Softwood Lignans by Supercritical Fluid Chromatography
by: Nikolay V. Ul’yanovskii, et al.
Published: (2023-08-01)

<i>Nor</i>-Lignans: Occurrence in Plants and Biological Activities—A Review
by: Claudio Frezza, et al.
Published: (2020-01-01)

Modular Synthesis and Biological Investigation of 5-Hydroxymethyl Dibenzyl Butyrolactones and Related Lignans
by: Samuel J. Davidson, et al.
Published: (2018-11-01)

Glycosyltransferase engineering and multi-glycosylation routes development facilitating synthesis of high-intensity sweetener mogrosides
by: Jiao Li, et al.
Published: (2022-10-01)

Identification and functional characterization of the dirigent gene family in Phryma leptostachya and the contribution of PlDIR1 in lignan biosynthesis
by: Yakun Pei, et al.
Published: (2023-05-01)

New Lignans from the Leaves and Stems of Kadsura philippinensis
by: Chang-Hung Chou, et al.
Published: (2013-06-01)

The influence of lignans on the quality of life of women of perimenopausal age
by: K G Serebrennikova, et al.
Published: (2018-06-01)

Lignans and Their Derivatives from Plants as Antivirals
by: Qinghua Cui, et al.
Published: (2020-01-01)