Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus

Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) have been detected in the urine of women with systemic lupus erythematosus (SLE). We evaluated the presence of these mycoplasma in the endocervix of women presenting SLE. A total of 40 SLE patients (mean age 40.2 years), and 51 healthy women (m...

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Main Authors: Alcyone A. Machado, Alessandro R. Zorzi, Ana Eugênia A. Gléria, Eduardo A. Donadi
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2001-06-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822001000300003&tlng=en
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author Alcyone A. Machado
Alessandro R. Zorzi
Ana Eugênia A. Gléria
Eduardo A. Donadi
author_facet Alcyone A. Machado
Alessandro R. Zorzi
Ana Eugênia A. Gléria
Eduardo A. Donadi
author_sort Alcyone A. Machado
collection DOAJ
description Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) have been detected in the urine of women with systemic lupus erythematosus (SLE). We evaluated the presence of these mycoplasma in the endocervix of women presenting SLE. A total of 40 SLE patients (mean age 40.2 years), and 51 healthy women (mean age 30.9 years), were studied. Endocervical swabs were cultured in specific liquid media for MH or UU, detected by a quantitative color assay, and considered positive at >10³ dilutions. Statistical analysis was performed using the two-tailed Fisher test. UU was detected in 52.5 % of patients and in 11.8% of controls (p= 0.000059). MH was detected in 20% of patients and 2% controls (p=0.003905). Both mycoplasmas were detected in 7.3% patients and 0% controls (p<0.000001). The results reported here corroborate the association of the mycoplasma infection and SLE. Thus, these agents may stimulate the production of autoreactive clones.
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spelling doaj.art-8203d7decaea4f329212f5d5b5223deb2022-12-22T00:14:47ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492001-06-01343243247Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosusAlcyone A. Machado0Alessandro R. Zorzi1Ana Eugênia A. Gléria2Eduardo A. Donadi3Universidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloUreaplasma urealyticum (UU) and Mycoplasma hominis (MH) have been detected in the urine of women with systemic lupus erythematosus (SLE). We evaluated the presence of these mycoplasma in the endocervix of women presenting SLE. A total of 40 SLE patients (mean age 40.2 years), and 51 healthy women (mean age 30.9 years), were studied. Endocervical swabs were cultured in specific liquid media for MH or UU, detected by a quantitative color assay, and considered positive at >10³ dilutions. Statistical analysis was performed using the two-tailed Fisher test. UU was detected in 52.5 % of patients and in 11.8% of controls (p= 0.000059). MH was detected in 20% of patients and 2% controls (p=0.003905). Both mycoplasmas were detected in 7.3% patients and 0% controls (p<0.000001). The results reported here corroborate the association of the mycoplasma infection and SLE. Thus, these agents may stimulate the production of autoreactive clones.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822001000300003&tlng=enMycoplasmaSystemic lupus erythematosusMycoplasma hominisUreaplasma urealyticumGenital infections
spellingShingle Alcyone A. Machado
Alessandro R. Zorzi
Ana Eugênia A. Gléria
Eduardo A. Donadi
Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus
Revista da Sociedade Brasileira de Medicina Tropical
Mycoplasma
Systemic lupus erythematosus
Mycoplasma hominis
Ureaplasma urealyticum
Genital infections
title Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus
title_full Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus
title_fullStr Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus
title_full_unstemmed Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus
title_short Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus
title_sort frequency of mycoplasma hominis and ureaplasma urealyticum infections in women with systemic lupus erythematosus
topic Mycoplasma
Systemic lupus erythematosus
Mycoplasma hominis
Ureaplasma urealyticum
Genital infections
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822001000300003&tlng=en
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