Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus
Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) have been detected in the urine of women with systemic lupus erythematosus (SLE). We evaluated the presence of these mycoplasma in the endocervix of women presenting SLE. A total of 40 SLE patients (mean age 40.2 years), and 51 healthy women (m...
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Sociedade Brasileira de Medicina Tropical (SBMT)
2001-06-01
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Series: | Revista da Sociedade Brasileira de Medicina Tropical |
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Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822001000300003&tlng=en |
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author | Alcyone A. Machado Alessandro R. Zorzi Ana Eugênia A. Gléria Eduardo A. Donadi |
author_facet | Alcyone A. Machado Alessandro R. Zorzi Ana Eugênia A. Gléria Eduardo A. Donadi |
author_sort | Alcyone A. Machado |
collection | DOAJ |
description | Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) have been detected in the urine of women with systemic lupus erythematosus (SLE). We evaluated the presence of these mycoplasma in the endocervix of women presenting SLE. A total of 40 SLE patients (mean age 40.2 years), and 51 healthy women (mean age 30.9 years), were studied. Endocervical swabs were cultured in specific liquid media for MH or UU, detected by a quantitative color assay, and considered positive at >10³ dilutions. Statistical analysis was performed using the two-tailed Fisher test. UU was detected in 52.5 % of patients and in 11.8% of controls (p= 0.000059). MH was detected in 20% of patients and 2% controls (p=0.003905). Both mycoplasmas were detected in 7.3% patients and 0% controls (p<0.000001). The results reported here corroborate the association of the mycoplasma infection and SLE. Thus, these agents may stimulate the production of autoreactive clones. |
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format | Article |
id | doaj.art-8203d7decaea4f329212f5d5b5223deb |
institution | Directory Open Access Journal |
issn | 1678-9849 |
language | English |
last_indexed | 2024-12-12T19:13:33Z |
publishDate | 2001-06-01 |
publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
record_format | Article |
series | Revista da Sociedade Brasileira de Medicina Tropical |
spelling | doaj.art-8203d7decaea4f329212f5d5b5223deb2022-12-22T00:14:47ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492001-06-01343243247Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosusAlcyone A. Machado0Alessandro R. Zorzi1Ana Eugênia A. Gléria2Eduardo A. Donadi3Universidade de São PauloUniversidade de São PauloUniversidade de São PauloUniversidade de São PauloUreaplasma urealyticum (UU) and Mycoplasma hominis (MH) have been detected in the urine of women with systemic lupus erythematosus (SLE). We evaluated the presence of these mycoplasma in the endocervix of women presenting SLE. A total of 40 SLE patients (mean age 40.2 years), and 51 healthy women (mean age 30.9 years), were studied. Endocervical swabs were cultured in specific liquid media for MH or UU, detected by a quantitative color assay, and considered positive at >10³ dilutions. Statistical analysis was performed using the two-tailed Fisher test. UU was detected in 52.5 % of patients and in 11.8% of controls (p= 0.000059). MH was detected in 20% of patients and 2% controls (p=0.003905). Both mycoplasmas were detected in 7.3% patients and 0% controls (p<0.000001). The results reported here corroborate the association of the mycoplasma infection and SLE. Thus, these agents may stimulate the production of autoreactive clones.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822001000300003&tlng=enMycoplasmaSystemic lupus erythematosusMycoplasma hominisUreaplasma urealyticumGenital infections |
spellingShingle | Alcyone A. Machado Alessandro R. Zorzi Ana Eugênia A. Gléria Eduardo A. Donadi Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus Revista da Sociedade Brasileira de Medicina Tropical Mycoplasma Systemic lupus erythematosus Mycoplasma hominis Ureaplasma urealyticum Genital infections |
title | Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus |
title_full | Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus |
title_fullStr | Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus |
title_full_unstemmed | Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus |
title_short | Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus |
title_sort | frequency of mycoplasma hominis and ureaplasma urealyticum infections in women with systemic lupus erythematosus |
topic | Mycoplasma Systemic lupus erythematosus Mycoplasma hominis Ureaplasma urealyticum Genital infections |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822001000300003&tlng=en |
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