Probiotics for the Prevention of Acute Respiratory-Tract Infections in Older People: Systematic Review
The aim of this systematic review was to present the indirect influence of probiotics on the incidence and duration of acute upper respiratory-tract infections in older people, by regulating the immune system. Eight randomized, placebo-controlled clinical trials met the inclusion criteria, consideri...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Healthcare |
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| Online Access: | https://www.mdpi.com/2227-9032/9/6/690 |
| _version_ | 1797531019819089920 |
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| author | Maja Strauss Dušanka Mičetić-Turk Maja Šikić Pogačar Sabina Fijan |
| author_facet | Maja Strauss Dušanka Mičetić-Turk Maja Šikić Pogačar Sabina Fijan |
| author_sort | Maja Strauss |
| collection | DOAJ |
| description | The aim of this systematic review was to present the indirect influence of probiotics on the incidence and duration of acute upper respiratory-tract infections in older people, by regulating the immune system. Eight randomized, placebo-controlled clinical trials met the inclusion criteria, considering the threshold of older people being 60 years and over. Single strain probiotics were used in all studies, including three probiotic strains used in fermented foods: <i>Lactobacillus delbrueckii</i> subsp. <i>bulgaricus</i> OLL1073R-1, <i>Lacticaseibacillus paracasei</i> subsp<i>. paracasei</i> CNCM I-1518 and <i>Lacticaseibacillus</i><i>paracasei</i> Shirota, and three probiotic strains used as food supplements: <i>Loigolactobacillus coryniformis</i> K8 CECT5711, <i>Bacillus subtilis</i> CU1 and <i>Lacticaseibacillus rhamnosus</i> GG. Current evidence showed that certain probiotic strains were better than a placebo in lowering the incidence or number of older people experiencing acute upper respiratory tract infections; however, not all probiotic strains were efficient, and not all studies reported statistically significant outcomes. More high quality large-scale properly controlled clinical studies focusing on older people are warranted. |
| first_indexed | 2024-03-10T10:38:09Z |
| format | Article |
| id | doaj.art-820528fcdc2044f488126d9dcc24b003 |
| institution | Directory Open Access Journal |
| issn | 2227-9032 |
| language | English |
| last_indexed | 2024-03-10T10:38:09Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Healthcare |
| spelling | doaj.art-820528fcdc2044f488126d9dcc24b0032023-11-21T23:09:00ZengMDPI AGHealthcare2227-90322021-06-019669010.3390/healthcare9060690Probiotics for the Prevention of Acute Respiratory-Tract Infections in Older People: Systematic ReviewMaja Strauss0Dušanka Mičetić-Turk1Maja Šikić Pogačar2Sabina Fijan3Faculty of Health Sciences, Institute for Health and Nutrition, University of Maribor, Žitna ulica 15, 2000 Maribor, SloveniaFaculty of Health Sciences, Institute for Health and Nutrition, University of Maribor, Žitna ulica 15, 2000 Maribor, SloveniaFaculty of Medicine, University of Maribor, Taborska ulica 8, 2000 Maribor, SloveniaFaculty of Health Sciences, Institute for Health and Nutrition, University of Maribor, Žitna ulica 15, 2000 Maribor, SloveniaThe aim of this systematic review was to present the indirect influence of probiotics on the incidence and duration of acute upper respiratory-tract infections in older people, by regulating the immune system. Eight randomized, placebo-controlled clinical trials met the inclusion criteria, considering the threshold of older people being 60 years and over. Single strain probiotics were used in all studies, including three probiotic strains used in fermented foods: <i>Lactobacillus delbrueckii</i> subsp. <i>bulgaricus</i> OLL1073R-1, <i>Lacticaseibacillus paracasei</i> subsp<i>. paracasei</i> CNCM I-1518 and <i>Lacticaseibacillus</i><i>paracasei</i> Shirota, and three probiotic strains used as food supplements: <i>Loigolactobacillus coryniformis</i> K8 CECT5711, <i>Bacillus subtilis</i> CU1 and <i>Lacticaseibacillus rhamnosus</i> GG. Current evidence showed that certain probiotic strains were better than a placebo in lowering the incidence or number of older people experiencing acute upper respiratory tract infections; however, not all probiotic strains were efficient, and not all studies reported statistically significant outcomes. More high quality large-scale properly controlled clinical studies focusing on older people are warranted.https://www.mdpi.com/2227-9032/9/6/690probioticsfermented foodsupper respiratory tract infectionsolder people |
| spellingShingle | Maja Strauss Dušanka Mičetić-Turk Maja Šikić Pogačar Sabina Fijan Probiotics for the Prevention of Acute Respiratory-Tract Infections in Older People: Systematic Review Healthcare probiotics fermented foods upper respiratory tract infections older people |
| title | Probiotics for the Prevention of Acute Respiratory-Tract Infections in Older People: Systematic Review |
| title_full | Probiotics for the Prevention of Acute Respiratory-Tract Infections in Older People: Systematic Review |
| title_fullStr | Probiotics for the Prevention of Acute Respiratory-Tract Infections in Older People: Systematic Review |
| title_full_unstemmed | Probiotics for the Prevention of Acute Respiratory-Tract Infections in Older People: Systematic Review |
| title_short | Probiotics for the Prevention of Acute Respiratory-Tract Infections in Older People: Systematic Review |
| title_sort | probiotics for the prevention of acute respiratory tract infections in older people systematic review |
| topic | probiotics fermented foods upper respiratory tract infections older people |
| url | https://www.mdpi.com/2227-9032/9/6/690 |
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