Educational performance and conduct problem trajectories from childhood to adolescence: Observational and genetic associations in a Brazilian birth cohort
Abstract Background Educational difficulties are an important potential influence on both the onset and course of children's conduct problems. This study evaluated the association between school failure and children's conduct problems in Brazil, a context with high rates of both conditions...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-12-01
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| Series: | JCPP Advances |
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| Online Access: | https://doi.org/10.1002/jcv2.12105 |
| _version_ | 1811295836991127552 |
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| author | Thais Martins‐Silva Andreas Bauer Alicia Matijasevich Iná Santos Aluísio Barros Ulf Ekelund Luciana Tovo‐Rodrigues Joseph Murray |
| author_facet | Thais Martins‐Silva Andreas Bauer Alicia Matijasevich Iná Santos Aluísio Barros Ulf Ekelund Luciana Tovo‐Rodrigues Joseph Murray |
| author_sort | Thais Martins‐Silva |
| collection | DOAJ |
| description | Abstract Background Educational difficulties are an important potential influence on both the onset and course of children's conduct problems. This study evaluated the association between school failure and children's conduct problems in Brazil, a context with high rates of both conditions, using both observational and genetic approaches. Methods Prospective, population‐based, birth cohort study in Pelotas city, Brazil. Parents reported on conduct problems four times between ages 4–15 years, and group‐based trajectory analysis was used to classify 3469 children into trajectories of childhood‐limited, early‐onset persistent, adolescence‐onset, or low conduct problems. School failure was measured as having repeated a school grade up to age 11, and a polygenic risk score (PRS) predicting educational attainment was calculated. Multinomial adjusted regression models were used to estimate the association between school failure (observational measure and the PRS) and conduct problem trajectories. To consider possible variation in effects of school failure by social context, interactions were tested with family income and school environment (using both observational and PRS methods). Results Children repeating a school grade had increased odds of being on to childhood‐limited (OR: 1.57; 95% CI 1.21; 2.03), adolescence‐onset (OR: 1.96; 95% CI 1.39; 2.75), or early‐onset persistent trajectory (OR: 2.99; 95% CI 1.85; 4.83), compared to the low conduct problem trajectory. School failure also predicted increased risk for early‐onset persistent problems versus the childhood‐limited problems (OR: 1.91; 95% CI 1.17; 3.09). Using a genetic PRS approach, similar findings were observed. Associations varied according to the school environment: school failure had larger effects on children in better school environments. Conclusion School performance, whether measured in terms of repeating school grades or genetic susceptibility, was consistently associated with trajectories of child conduct problems into mid‐adolescence. We also found a larger association for children in better school environments. |
| first_indexed | 2024-04-13T05:39:29Z |
| format | Article |
| id | doaj.art-8206fc712ed84f53872fffb793388dbf |
| institution | Directory Open Access Journal |
| issn | 2692-9384 |
| language | English |
| last_indexed | 2024-04-13T05:39:29Z |
| publishDate | 2022-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | JCPP Advances |
| spelling | doaj.art-8206fc712ed84f53872fffb793388dbf2022-12-22T03:00:10ZengWileyJCPP Advances2692-93842022-12-0124n/an/a10.1002/jcv2.12105Educational performance and conduct problem trajectories from childhood to adolescence: Observational and genetic associations in a Brazilian birth cohortThais Martins‐Silva0Andreas Bauer1Alicia Matijasevich2Iná Santos3Aluísio Barros4Ulf Ekelund5Luciana Tovo‐Rodrigues6Joseph Murray7Human Development and Violence Research Centre (DOVE) Federal University of Pelotas Pelotas BrazilHuman Development and Violence Research Centre (DOVE) Federal University of Pelotas Pelotas BrazilPost‐Graduate Program in Epidemiology Federal University of Pelotas Pelotas BrazilPost‐Graduate Program in Epidemiology Federal University of Pelotas Pelotas BrazilPost‐Graduate Program in Epidemiology Federal University of Pelotas Pelotas BrazilDepartment of Sport Medicine Norwegian School of Sport Sciences Oslo NorwayHuman Development and Violence Research Centre (DOVE) Federal University of Pelotas Pelotas BrazilHuman Development and Violence Research Centre (DOVE) Federal University of Pelotas Pelotas BrazilAbstract Background Educational difficulties are an important potential influence on both the onset and course of children's conduct problems. This study evaluated the association between school failure and children's conduct problems in Brazil, a context with high rates of both conditions, using both observational and genetic approaches. Methods Prospective, population‐based, birth cohort study in Pelotas city, Brazil. Parents reported on conduct problems four times between ages 4–15 years, and group‐based trajectory analysis was used to classify 3469 children into trajectories of childhood‐limited, early‐onset persistent, adolescence‐onset, or low conduct problems. School failure was measured as having repeated a school grade up to age 11, and a polygenic risk score (PRS) predicting educational attainment was calculated. Multinomial adjusted regression models were used to estimate the association between school failure (observational measure and the PRS) and conduct problem trajectories. To consider possible variation in effects of school failure by social context, interactions were tested with family income and school environment (using both observational and PRS methods). Results Children repeating a school grade had increased odds of being on to childhood‐limited (OR: 1.57; 95% CI 1.21; 2.03), adolescence‐onset (OR: 1.96; 95% CI 1.39; 2.75), or early‐onset persistent trajectory (OR: 2.99; 95% CI 1.85; 4.83), compared to the low conduct problem trajectory. School failure also predicted increased risk for early‐onset persistent problems versus the childhood‐limited problems (OR: 1.91; 95% CI 1.17; 3.09). Using a genetic PRS approach, similar findings were observed. Associations varied according to the school environment: school failure had larger effects on children in better school environments. Conclusion School performance, whether measured in terms of repeating school grades or genetic susceptibility, was consistently associated with trajectories of child conduct problems into mid‐adolescence. We also found a larger association for children in better school environments.https://doi.org/10.1002/jcv2.12105conduct disorderseducationgene‐environment interactiongeneticslongitudinal studies |
| spellingShingle | Thais Martins‐Silva Andreas Bauer Alicia Matijasevich Iná Santos Aluísio Barros Ulf Ekelund Luciana Tovo‐Rodrigues Joseph Murray Educational performance and conduct problem trajectories from childhood to adolescence: Observational and genetic associations in a Brazilian birth cohort JCPP Advances conduct disorders education gene‐environment interaction genetics longitudinal studies |
| title | Educational performance and conduct problem trajectories from childhood to adolescence: Observational and genetic associations in a Brazilian birth cohort |
| title_full | Educational performance and conduct problem trajectories from childhood to adolescence: Observational and genetic associations in a Brazilian birth cohort |
| title_fullStr | Educational performance and conduct problem trajectories from childhood to adolescence: Observational and genetic associations in a Brazilian birth cohort |
| title_full_unstemmed | Educational performance and conduct problem trajectories from childhood to adolescence: Observational and genetic associations in a Brazilian birth cohort |
| title_short | Educational performance and conduct problem trajectories from childhood to adolescence: Observational and genetic associations in a Brazilian birth cohort |
| title_sort | educational performance and conduct problem trajectories from childhood to adolescence observational and genetic associations in a brazilian birth cohort |
| topic | conduct disorders education gene‐environment interaction genetics longitudinal studies |
| url | https://doi.org/10.1002/jcv2.12105 |
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